Experiment: R2A with Lomefloxacin 0.00075 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt RR42_RS24300 and RR42_RS24305 are separated by 18 nucleotides
RR42_RS24300: RR42_RS24300 - acetyl-CoA acetyltransferase, at 779,910 to 781,097
_RS24300
RR42_RS24305: RR42_RS24305 - 3-hydroxybutyryl-CoA dehydrogenase, at 781,116 to 781,967
_RS24305
Position (kb) 779
780
781
782 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 779.139 kb on + strand at 779.140 kb on - strand at 779.140 kb on - strand at 779.254 kb on - strand at 779.331 kb on - strand at 779.427 kb on + strand at 779.501 kb on + strand at 779.501 kb on + strand at 779.501 kb on + strand at 779.501 kb on + strand at 779.502 kb on - strand at 779.536 kb on + strand at 779.536 kb on + strand at 779.536 kb on + strand at 779.536 kb on + strand at 779.536 kb on + strand at 779.536 kb on + strand at 779.536 kb on + strand at 779.536 kb on + strand at 779.585 kb on - strand at 779.585 kb on - strand at 779.585 kb on - strand at 779.596 kb on + strand at 779.667 kb on + strand at 779.668 kb on - strand at 779.668 kb on - strand at 779.668 kb on - strand at 779.668 kb on - strand at 779.700 kb on + strand at 779.700 kb on + strand at 779.701 kb on - strand at 779.701 kb on - strand at 779.704 kb on + strand at 779.704 kb on + strand at 779.704 kb on + strand at 779.762 kb on - strand at 779.813 kb on + strand at 779.814 kb on - strand at 779.814 kb on - strand at 779.814 kb on - strand at 779.848 kb on + strand at 779.850 kb on - strand at 779.850 kb on - strand at 779.861 kb on + strand at 779.862 kb on - strand at 779.893 kb on + strand at 779.928 kb on + strand at 779.928 kb on + strand at 779.928 kb on + strand at 779.928 kb on + strand at 779.929 kb on - strand at 779.929 kb on - strand at 779.929 kb on - strand at 779.961 kb on - strand at 779.978 kb on + strand at 779.986 kb on + strand at 779.986 kb on + strand at 779.987 kb on - strand at 779.987 kb on - strand at 779.987 kb on - strand at 780.108 kb on + strand, within RR42_RS24300 at 780.108 kb on + strand, within RR42_RS24300 at 780.108 kb on + strand, within RR42_RS24300 at 780.108 kb on + strand, within RR42_RS24300 at 780.108 kb on + strand, within RR42_RS24300 at 780.108 kb on + strand, within RR42_RS24300 at 780.109 kb on - strand, within RR42_RS24300 at 780.109 kb on - strand, within RR42_RS24300 at 780.109 kb on - strand, within RR42_RS24300 at 780.109 kb on - strand, within RR42_RS24300 at 780.109 kb on - strand, within RR42_RS24300 at 780.109 kb on - strand, within RR42_RS24300 at 780.109 kb on - strand, within RR42_RS24300 at 780.285 kb on + strand, within RR42_RS24300 at 780.286 kb on + strand, within RR42_RS24300 at 780.286 kb on - strand, within RR42_RS24300 at 780.286 kb on - strand, within RR42_RS24300 at 780.286 kb on - strand, within RR42_RS24300 at 780.293 kb on - strand, within RR42_RS24300 at 780.342 kb on + strand, within RR42_RS24300 at 780.343 kb on - strand, within RR42_RS24300 at 780.344 kb on + strand, within RR42_RS24300 at 780.344 kb on + strand, within RR42_RS24300 at 780.344 kb on + strand, within RR42_RS24300 at 780.344 kb on + strand, within RR42_RS24300 at 780.345 kb on - strand, within RR42_RS24300 at 780.345 kb on - strand, within RR42_RS24300 at 780.345 kb on - strand, within RR42_RS24300 at 780.345 kb on - strand, within RR42_RS24300 at 780.345 kb on - strand, within RR42_RS24300 at 780.345 kb on - strand, within RR42_RS24300 at 780.403 kb on - strand, within RR42_RS24300 at 780.403 kb on - strand, within RR42_RS24300 at 780.403 kb on - strand, within RR42_RS24300 at 780.501 kb on - strand, within RR42_RS24300 at 780.547 kb on + strand, within RR42_RS24300 at 780.547 kb on + strand, within RR42_RS24300 at 780.548 kb on - strand, within RR42_RS24300 at 780.548 kb on - strand, within RR42_RS24300 at 780.548 kb on - strand, within RR42_RS24300 at 780.548 kb on - strand, within RR42_RS24300 at 780.548 kb on - strand, within RR42_RS24300 at 780.640 kb on + strand, within RR42_RS24300 at 780.685 kb on + strand, within RR42_RS24300 at 780.686 kb on - strand, within RR42_RS24300 at 780.686 kb on - strand, within RR42_RS24300 at 780.686 kb on - strand, within RR42_RS24300 at 780.688 kb on + strand, within RR42_RS24300 at 780.688 kb on + strand, within RR42_RS24300 at 780.689 kb on - strand, within RR42_RS24300 at 780.838 kb on + strand, within RR42_RS24300 at 780.838 kb on + strand, within RR42_RS24300 at 780.838 kb on + strand, within RR42_RS24300 at 780.853 kb on + strand, within RR42_RS24300 at 780.853 kb on + strand, within RR42_RS24300 at 780.853 kb on + strand, within RR42_RS24300 at 780.854 kb on - strand, within RR42_RS24300 at 780.888 kb on + strand, within RR42_RS24300 at 780.888 kb on + strand, within RR42_RS24300 at 780.889 kb on - strand, within RR42_RS24300 at 780.889 kb on - strand, within RR42_RS24300 at 780.928 kb on + strand, within RR42_RS24300 at 780.929 kb on - strand, within RR42_RS24300 at 781.005 kb on + strand at 781.006 kb on - strand at 781.006 kb on - strand at 781.006 kb on - strand at 781.006 kb on - strand at 781.006 kb on - strand at 781.006 kb on - strand at 781.021 kb on + strand at 781.022 kb on - strand at 781.070 kb on + strand at 781.070 kb on + strand at 781.122 kb on - strand at 781.130 kb on + strand at 781.130 kb on + strand at 781.131 kb on - strand at 781.131 kb on - strand at 781.166 kb on + strand at 781.167 kb on - strand at 781.231 kb on + strand, within RR42_RS24305 at 781.259 kb on + strand, within RR42_RS24305 at 781.259 kb on + strand, within RR42_RS24305 at 781.278 kb on - strand, within RR42_RS24305 at 781.335 kb on - strand, within RR42_RS24305 at 781.335 kb on - strand, within RR42_RS24305 at 781.335 kb on - strand, within RR42_RS24305 at 781.344 kb on + strand, within RR42_RS24305 at 781.346 kb on + strand, within RR42_RS24305 at 781.346 kb on + strand, within RR42_RS24305 at 781.347 kb on - strand, within RR42_RS24305 at 781.347 kb on - strand, within RR42_RS24305 at 781.347 kb on - strand, within RR42_RS24305 at 781.439 kb on - strand, within RR42_RS24305 at 781.439 kb on - strand, within RR42_RS24305 at 781.456 kb on + strand, within RR42_RS24305 at 781.651 kb on + strand, within RR42_RS24305 at 781.688 kb on + strand, within RR42_RS24305 at 781.689 kb on - strand, within RR42_RS24305 at 781.689 kb on - strand, within RR42_RS24305 at 781.706 kb on + strand, within RR42_RS24305 at 781.707 kb on - strand, within RR42_RS24305 at 781.830 kb on - strand, within RR42_RS24305 at 781.858 kb on - strand, within RR42_RS24305 at 781.900 kb on + strand at 781.900 kb on + strand at 781.901 kb on - strand at 781.901 kb on - strand at 781.901 kb on - strand at 781.934 kb on + strand at 781.935 kb on - strand at 781.935 kb on - strand at 781.935 kb on - strand at 781.953 kb on + strand at 781.953 kb on + strand at 781.953 kb on + strand at 781.953 kb on + strand at 781.953 kb on + strand at 781.954 kb on - strand at 781.954 kb on - strand at 781.954 kb on - strand at 781.959 kb on + strand at 781.959 kb on + strand at 781.959 kb on + strand at 781.959 kb on + strand at 781.978 kb on + strand at 781.978 kb on + strand at 781.992 kb on + strand at 781.993 kb on - strand at 782.057 kb on + strand at 782.057 kb on + strand at 782.057 kb on + strand at 782.058 kb on - strand at 782.076 kb on + strand at 782.076 kb on + strand at 782.076 kb on + strand at 782.076 kb on + strand at 782.076 kb on + strand at 782.077 kb on - strand at 782.077 kb on - strand at 782.077 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction R2A with Lomefloxacin 0.00075 mM remove 779,139 + -0.0 779,140 - -0.5 779,140 - -0.1 779,254 - +0.0 779,331 - -0.5 779,427 + -0.2 779,501 + +0.5 779,501 + -0.5 779,501 + +1.2 779,501 + -0.6 779,502 - -1.5 779,536 + -0.0 779,536 + +1.1 779,536 + +1.3 779,536 + +1.0 779,536 + -0.0 779,536 + -0.5 779,536 + -0.1 779,536 + +0.1 779,585 - +0.3 779,585 - +0.1 779,585 - +0.6 779,596 + +0.0 779,667 + -1.9 779,668 - +0.9 779,668 - -1.4 779,668 - +0.4 779,668 - +0.4 779,700 + +1.2 779,700 + -0.5 779,701 - +0.8 779,701 - +0.7 779,704 + -0.4 779,704 + -0.2 779,704 + +0.3 779,762 - +0.2 779,813 + -1.3 779,814 - +0.8 779,814 - +0.9 779,814 - +0.9 779,848 + +1.2 779,850 - -0.0 779,850 - +0.5 779,861 + -0.2 779,862 - -1.0 779,893 + +1.5 779,928 + -0.7 779,928 + +0.6 779,928 + -0.2 779,928 + +0.1 779,929 - +0.4 779,929 - -0.1 779,929 - -0.1 779,961 - +0.1 779,978 + -1.4 779,986 + +0.4 779,986 + +0.3 779,987 - -0.2 779,987 - -0.5 779,987 - -0.3 780,108 + RR42_RS24300 0.17 +0.4 780,108 + RR42_RS24300 0.17 -0.0 780,108 + RR42_RS24300 0.17 +0.3 780,108 + RR42_RS24300 0.17 +0.3 780,108 + RR42_RS24300 0.17 -0.4 780,108 + RR42_RS24300 0.17 -0.1 780,109 - RR42_RS24300 0.17 +0.1 780,109 - RR42_RS24300 0.17 -1.0 780,109 - RR42_RS24300 0.17 -0.7 780,109 - RR42_RS24300 0.17 +0.4 780,109 - RR42_RS24300 0.17 +0.6 780,109 - RR42_RS24300 0.17 -1.0 780,109 - RR42_RS24300 0.17 +0.9 780,285 + RR42_RS24300 0.32 +1.0 780,286 + RR42_RS24300 0.32 +0.1 780,286 - RR42_RS24300 0.32 -0.3 780,286 - RR42_RS24300 0.32 -0.3 780,286 - RR42_RS24300 0.32 -0.4 780,293 - RR42_RS24300 0.32 -0.7 780,342 + RR42_RS24300 0.36 +0.1 780,343 - RR42_RS24300 0.36 -0.7 780,344 + RR42_RS24300 0.37 -1.7 780,344 + RR42_RS24300 0.37 +0.0 780,344 + RR42_RS24300 0.37 -0.3 780,344 + RR42_RS24300 0.37 -0.9 780,345 - RR42_RS24300 0.37 -3.1 780,345 - RR42_RS24300 0.37 +0.9 780,345 - RR42_RS24300 0.37 +0.5 780,345 - RR42_RS24300 0.37 +0.1 780,345 - RR42_RS24300 0.37 +0.0 780,345 - RR42_RS24300 0.37 +0.1 780,403 - RR42_RS24300 0.41 -2.2 780,403 - RR42_RS24300 0.41 +0.4 780,403 - RR42_RS24300 0.41 +1.3 780,501 - RR42_RS24300 0.50 +0.1 780,547 + RR42_RS24300 0.54 -0.3 780,547 + RR42_RS24300 0.54 +0.2 780,548 - RR42_RS24300 0.54 +1.0 780,548 - RR42_RS24300 0.54 +0.8 780,548 - RR42_RS24300 0.54 +1.2 780,548 - RR42_RS24300 0.54 +0.3 780,548 - RR42_RS24300 0.54 +1.7 780,640 + RR42_RS24300 0.61 +0.4 780,685 + RR42_RS24300 0.65 -1.3 780,686 - RR42_RS24300 0.65 -1.2 780,686 - RR42_RS24300 0.65 +1.8 780,686 - RR42_RS24300 0.65 +0.4 780,688 + RR42_RS24300 0.65 +0.9 780,688 + RR42_RS24300 0.65 -0.6 780,689 - RR42_RS24300 0.66 -0.4 780,838 + RR42_RS24300 0.78 -0.0 780,838 + RR42_RS24300 0.78 +1.2 780,838 + RR42_RS24300 0.78 +1.4 780,853 + RR42_RS24300 0.79 -0.2 780,853 + RR42_RS24300 0.79 +0.3 780,853 + RR42_RS24300 0.79 -0.4 780,854 - RR42_RS24300 0.79 +0.0 780,888 + RR42_RS24300 0.82 +1.0 780,888 + RR42_RS24300 0.82 +2.1 780,889 - RR42_RS24300 0.82 -0.5 780,889 - RR42_RS24300 0.82 -1.3 780,928 + RR42_RS24300 0.86 +0.2 780,929 - RR42_RS24300 0.86 +0.4 781,005 + +0.4 781,006 - -0.3 781,006 - +0.1 781,006 - +1.0 781,006 - +0.1 781,006 - -0.7 781,006 - -0.3 781,021 + +0.2 781,022 - -0.5 781,070 + -0.2 781,070 + +0.6 781,122 - +0.7 781,130 + -0.6 781,130 + -0.6 781,131 - +1.0 781,131 - +0.9 781,166 + -1.4 781,167 - +0.2 781,231 + RR42_RS24305 0.13 +0.7 781,259 + RR42_RS24305 0.17 +0.6 781,259 + RR42_RS24305 0.17 +0.5 781,278 - RR42_RS24305 0.19 +0.9 781,335 - RR42_RS24305 0.26 +1.5 781,335 - RR42_RS24305 0.26 +0.1 781,335 - RR42_RS24305 0.26 -2.1 781,344 + RR42_RS24305 0.27 +1.3 781,346 + RR42_RS24305 0.27 +0.1 781,346 + RR42_RS24305 0.27 +0.5 781,347 - RR42_RS24305 0.27 +0.8 781,347 - RR42_RS24305 0.27 +0.0 781,347 - RR42_RS24305 0.27 +0.3 781,439 - RR42_RS24305 0.38 +1.1 781,439 - RR42_RS24305 0.38 +0.6 781,456 + RR42_RS24305 0.40 -1.1 781,651 + RR42_RS24305 0.63 -0.1 781,688 + RR42_RS24305 0.67 +0.5 781,689 - RR42_RS24305 0.67 -1.2 781,689 - RR42_RS24305 0.67 +0.1 781,706 + RR42_RS24305 0.69 -0.8 781,707 - RR42_RS24305 0.69 +0.7 781,830 - RR42_RS24305 0.84 +1.5 781,858 - RR42_RS24305 0.87 -2.3 781,900 + +0.2 781,900 + -0.5 781,901 - +0.3 781,901 - +0.1 781,901 - +0.3 781,934 + +2.1 781,935 - +0.1 781,935 - +0.7 781,935 - -1.7 781,953 + -0.3 781,953 + -0.1 781,953 + +0.1 781,953 + -0.6 781,953 + +0.8 781,954 - +0.4 781,954 - +0.4 781,954 - -0.7 781,959 + +0.1 781,959 + +0.1 781,959 + -0.0 781,959 + +0.2 781,978 + +0.2 781,978 + -1.2 781,992 + -0.2 781,993 - +0.1 782,057 + -0.3 782,057 + -0.8 782,057 + -0.2 782,058 - -0.2 782,076 + +1.9 782,076 + -0.0 782,076 + -0.5 782,076 + +1.9 782,076 + +0.7 782,077 - -0.8 782,077 - +0.8 782,077 - +0.2
Or see this region's nucleotide sequence