Experiment: R2A with Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt RR42_RS29640 and RR42_RS29645 are separated by 143 nucleotides RR42_RS29645 and RR42_RS29650 are separated by 276 nucleotides RR42_RS29650 and RR42_RS29655 are separated by 3 nucleotides
RR42_RS29640: RR42_RS29640 - integrase, at 2,017,601 to 2,019,124
_RS29640
RR42_RS29645: RR42_RS29645 - ABC transporter substrate-binding protein, at 2,019,268 to 2,019,867
_RS29645
RR42_RS29650: RR42_RS29650 - histidine ABC transporter permease, at 2,020,144 to 2,020,833
_RS29650
RR42_RS29655: RR42_RS29655 - amino acid ABC transporter permease, at 2,020,837 to 2,021,550
_RS29655
Position (kb)
2019
2020 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 2018.366 kb on + strand, within RR42_RS29640 at 2018.367 kb on - strand, within RR42_RS29640 at 2018.367 kb on - strand, within RR42_RS29640 at 2018.367 kb on - strand, within RR42_RS29640 at 2018.367 kb on - strand, within RR42_RS29640 at 2018.391 kb on + strand, within RR42_RS29640 at 2018.392 kb on - strand, within RR42_RS29640 at 2018.393 kb on + strand, within RR42_RS29640 at 2018.393 kb on + strand, within RR42_RS29640 at 2018.393 kb on + strand, within RR42_RS29640 at 2018.393 kb on + strand, within RR42_RS29640 at 2018.394 kb on - strand, within RR42_RS29640 at 2018.394 kb on - strand, within RR42_RS29640 at 2018.394 kb on - strand, within RR42_RS29640 at 2018.394 kb on - strand, within RR42_RS29640 at 2018.394 kb on - strand, within RR42_RS29640 at 2018.421 kb on + strand, within RR42_RS29640 at 2018.532 kb on + strand, within RR42_RS29640 at 2018.533 kb on - strand, within RR42_RS29640 at 2018.533 kb on - strand, within RR42_RS29640 at 2018.608 kb on - strand, within RR42_RS29640 at 2018.608 kb on - strand, within RR42_RS29640 at 2018.757 kb on + strand, within RR42_RS29640 at 2018.758 kb on - strand, within RR42_RS29640 at 2018.758 kb on - strand, within RR42_RS29640 at 2018.758 kb on - strand, within RR42_RS29640 at 2018.758 kb on - strand, within RR42_RS29640 at 2018.776 kb on + strand, within RR42_RS29640 at 2018.776 kb on + strand, within RR42_RS29640 at 2018.776 kb on + strand, within RR42_RS29640 at 2018.776 kb on + strand, within RR42_RS29640 at 2018.776 kb on + strand, within RR42_RS29640 at 2018.777 kb on - strand, within RR42_RS29640 at 2018.777 kb on - strand, within RR42_RS29640 at 2018.777 kb on - strand, within RR42_RS29640 at 2018.778 kb on + strand, within RR42_RS29640 at 2018.778 kb on + strand, within RR42_RS29640 at 2018.784 kb on + strand, within RR42_RS29640 at 2018.784 kb on + strand, within RR42_RS29640 at 2018.785 kb on - strand, within RR42_RS29640 at 2018.814 kb on + strand, within RR42_RS29640 at 2018.814 kb on + strand, within RR42_RS29640 at 2018.815 kb on - strand, within RR42_RS29640 at 2018.877 kb on + strand, within RR42_RS29640 at 2018.878 kb on - strand, within RR42_RS29640 at 2018.878 kb on - strand, within RR42_RS29640 at 2018.892 kb on + strand, within RR42_RS29640 at 2018.950 kb on + strand, within RR42_RS29640 at 2018.950 kb on + strand, within RR42_RS29640 at 2018.950 kb on + strand, within RR42_RS29640 at 2018.990 kb on + strand at 2019.000 kb on + strand at 2019.000 kb on + strand at 2019.001 kb on - strand at 2019.001 kb on - strand at 2019.001 kb on - strand at 2019.001 kb on - strand at 2019.001 kb on - strand at 2019.001 kb on - strand at 2019.001 kb on - strand at 2019.023 kb on + strand at 2019.023 kb on + strand at 2019.023 kb on + strand at 2019.024 kb on - strand at 2019.024 kb on - strand at 2019.024 kb on - strand at 2019.024 kb on - strand at 2019.024 kb on - strand at 2019.074 kb on - strand at 2019.152 kb on + strand at 2019.152 kb on + strand at 2019.153 kb on - strand at 2019.287 kb on + strand at 2019.287 kb on + strand at 2019.287 kb on + strand at 2019.288 kb on - strand at 2019.409 kb on + strand, within RR42_RS29645 at 2019.410 kb on - strand, within RR42_RS29645 at 2019.459 kb on + strand, within RR42_RS29645 at 2019.459 kb on + strand, within RR42_RS29645 at 2019.494 kb on + strand, within RR42_RS29645 at 2019.494 kb on + strand, within RR42_RS29645 at 2019.494 kb on + strand, within RR42_RS29645 at 2019.495 kb on - strand, within RR42_RS29645 at 2019.495 kb on - strand, within RR42_RS29645 at 2019.495 kb on - strand, within RR42_RS29645 at 2019.520 kb on + strand, within RR42_RS29645 at 2019.520 kb on + strand, within RR42_RS29645 at 2019.520 kb on + strand, within RR42_RS29645 at 2019.520 kb on + strand, within RR42_RS29645 at 2019.521 kb on - strand, within RR42_RS29645 at 2019.521 kb on - strand, within RR42_RS29645 at 2019.521 kb on - strand, within RR42_RS29645 at 2019.609 kb on + strand, within RR42_RS29645 at 2019.609 kb on + strand, within RR42_RS29645 at 2019.702 kb on + strand, within RR42_RS29645 at 2019.735 kb on + strand, within RR42_RS29645 at 2019.736 kb on - strand, within RR42_RS29645 at 2019.736 kb on - strand, within RR42_RS29645 at 2019.736 kb on - strand, within RR42_RS29645 at 2019.777 kb on + strand, within RR42_RS29645 at 2019.777 kb on + strand, within RR42_RS29645 at 2019.777 kb on + strand, within RR42_RS29645 at 2019.778 kb on - strand, within RR42_RS29645 at 2019.778 kb on - strand, within RR42_RS29645 at 2019.796 kb on - strand, within RR42_RS29645 at 2019.796 kb on - strand, within RR42_RS29645 at 2019.817 kb on + strand at 2019.817 kb on + strand at 2019.818 kb on - strand at 2019.818 kb on - strand at 2019.838 kb on + strand at 2019.838 kb on + strand at 2019.856 kb on + strand at 2019.857 kb on - strand at 2019.857 kb on - strand at 2019.857 kb on - strand at 2019.857 kb on - strand at 2019.862 kb on - strand at 2019.862 kb on - strand at 2019.938 kb on + strand at 2019.939 kb on - strand at 2019.939 kb on - strand at 2019.939 kb on - strand at 2019.973 kb on + strand at 2019.974 kb on - strand at 2019.974 kb on - strand at 2019.977 kb on + strand at 2019.977 kb on + strand at 2019.977 kb on + strand at 2019.978 kb on - strand at 2019.978 kb on - strand at 2019.978 kb on - strand at 2019.978 kb on - strand at 2019.978 kb on - strand at 2019.978 kb on - strand at 2019.985 kb on - strand at 2020.000 kb on + strand at 2020.014 kb on + strand at 2020.015 kb on - strand at 2020.015 kb on - strand at 2020.103 kb on + strand at 2020.104 kb on - strand at 2020.104 kb on - strand at 2020.154 kb on - strand at 2020.154 kb on - strand at 2020.172 kb on + strand at 2020.172 kb on + strand at 2020.188 kb on + strand at 2020.194 kb on + strand at 2020.195 kb on - strand at 2020.293 kb on + strand, within RR42_RS29650 at 2020.294 kb on - strand, within RR42_RS29650 at 2020.294 kb on - strand, within RR42_RS29650 at 2020.294 kb on - strand, within RR42_RS29650 at 2020.294 kb on - strand, within RR42_RS29650 at 2020.294 kb on - strand, within RR42_RS29650 at 2020.300 kb on + strand, within RR42_RS29650 at 2020.301 kb on - strand, within RR42_RS29650 at 2020.301 kb on - strand, within RR42_RS29650 at 2020.311 kb on + strand, within RR42_RS29650 at 2020.337 kb on + strand, within RR42_RS29650 at 2020.337 kb on + strand, within RR42_RS29650 at 2020.337 kb on + strand, within RR42_RS29650 at 2020.439 kb on + strand, within RR42_RS29650 at 2020.465 kb on + strand, within RR42_RS29650 at 2020.466 kb on - strand, within RR42_RS29650 at 2020.466 kb on - strand, within RR42_RS29650 at 2020.470 kb on + strand, within RR42_RS29650 at 2020.470 kb on + strand, within RR42_RS29650 at 2020.470 kb on + strand, within RR42_RS29650 at 2020.534 kb on + strand, within RR42_RS29650 at 2020.535 kb on - strand, within RR42_RS29650 at 2020.556 kb on + strand, within RR42_RS29650 at 2020.557 kb on - strand, within RR42_RS29650 at 2020.748 kb on - strand, within RR42_RS29650 at 2020.748 kb on - strand, within RR42_RS29650 at 2020.756 kb on - strand, within RR42_RS29650 at 2020.801 kb on + strand at 2020.801 kb on + strand at 2020.802 kb on - strand at 2020.802 kb on - strand at 2020.831 kb on + strand at 2020.832 kb on - strand at 2020.845 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction R2A with Vancomycin 0.5 mg/ml remove 2,018,366 + RR42_RS29640 0.50 -0.8 2,018,367 - RR42_RS29640 0.50 +0.6 2,018,367 - RR42_RS29640 0.50 +1.0 2,018,367 - RR42_RS29640 0.50 +1.1 2,018,367 - RR42_RS29640 0.50 -0.5 2,018,391 + RR42_RS29640 0.52 -0.0 2,018,392 - RR42_RS29640 0.52 +1.7 2,018,393 + RR42_RS29640 0.52 -0.2 2,018,393 + RR42_RS29640 0.52 -0.2 2,018,393 + RR42_RS29640 0.52 +0.4 2,018,393 + RR42_RS29640 0.52 -0.3 2,018,394 - RR42_RS29640 0.52 -1.3 2,018,394 - RR42_RS29640 0.52 -0.8 2,018,394 - RR42_RS29640 0.52 +0.7 2,018,394 - RR42_RS29640 0.52 -1.4 2,018,394 - RR42_RS29640 0.52 +0.6 2,018,421 + RR42_RS29640 0.54 +0.1 2,018,532 + RR42_RS29640 0.61 +0.1 2,018,533 - RR42_RS29640 0.61 +0.7 2,018,533 - RR42_RS29640 0.61 +1.5 2,018,608 - RR42_RS29640 0.66 +1.3 2,018,608 - RR42_RS29640 0.66 -0.9 2,018,757 + RR42_RS29640 0.76 -0.6 2,018,758 - RR42_RS29640 0.76 -0.3 2,018,758 - RR42_RS29640 0.76 +0.2 2,018,758 - RR42_RS29640 0.76 +1.2 2,018,758 - RR42_RS29640 0.76 -0.2 2,018,776 + RR42_RS29640 0.77 -0.6 2,018,776 + RR42_RS29640 0.77 +0.8 2,018,776 + RR42_RS29640 0.77 +1.2 2,018,776 + RR42_RS29640 0.77 +0.5 2,018,776 + RR42_RS29640 0.77 -0.7 2,018,777 - RR42_RS29640 0.77 +0.1 2,018,777 - RR42_RS29640 0.77 +2.0 2,018,777 - RR42_RS29640 0.77 -1.9 2,018,778 + RR42_RS29640 0.77 +1.2 2,018,778 + RR42_RS29640 0.77 +0.0 2,018,784 + RR42_RS29640 0.78 +0.6 2,018,784 + RR42_RS29640 0.78 +0.1 2,018,785 - RR42_RS29640 0.78 +0.5 2,018,814 + RR42_RS29640 0.80 -0.9 2,018,814 + RR42_RS29640 0.80 +0.9 2,018,815 - RR42_RS29640 0.80 -0.8 2,018,877 + RR42_RS29640 0.84 -0.9 2,018,878 - RR42_RS29640 0.84 -0.9 2,018,878 - RR42_RS29640 0.84 -0.0 2,018,892 + RR42_RS29640 0.85 -1.6 2,018,950 + RR42_RS29640 0.89 -0.7 2,018,950 + RR42_RS29640 0.89 -0.3 2,018,950 + RR42_RS29640 0.89 -0.0 2,018,990 + -0.2 2,019,000 + -0.3 2,019,000 + -0.6 2,019,001 - +0.3 2,019,001 - +0.2 2,019,001 - -0.1 2,019,001 - +1.0 2,019,001 - +0.8 2,019,001 - +0.3 2,019,001 - -0.3 2,019,023 + +0.2 2,019,023 + +0.7 2,019,023 + -1.6 2,019,024 - +0.8 2,019,024 - +0.2 2,019,024 - -0.8 2,019,024 - -0.4 2,019,024 - -1.2 2,019,074 - +0.6 2,019,152 + -1.2 2,019,152 + +0.9 2,019,153 - +0.5 2,019,287 + -1.8 2,019,287 + +0.5 2,019,287 + +0.3 2,019,288 - +0.8 2,019,409 + RR42_RS29645 0.23 +0.3 2,019,410 - RR42_RS29645 0.24 +1.2 2,019,459 + RR42_RS29645 0.32 -1.6 2,019,459 + RR42_RS29645 0.32 +1.5 2,019,494 + RR42_RS29645 0.38 +0.0 2,019,494 + RR42_RS29645 0.38 -1.0 2,019,494 + RR42_RS29645 0.38 +0.8 2,019,495 - RR42_RS29645 0.38 -0.9 2,019,495 - RR42_RS29645 0.38 +0.4 2,019,495 - RR42_RS29645 0.38 +0.6 2,019,520 + RR42_RS29645 0.42 -0.3 2,019,520 + RR42_RS29645 0.42 -0.5 2,019,520 + RR42_RS29645 0.42 -0.9 2,019,520 + RR42_RS29645 0.42 -0.2 2,019,521 - RR42_RS29645 0.42 +0.2 2,019,521 - RR42_RS29645 0.42 -0.4 2,019,521 - RR42_RS29645 0.42 +1.5 2,019,609 + RR42_RS29645 0.57 +0.0 2,019,609 + RR42_RS29645 0.57 +0.2 2,019,702 + RR42_RS29645 0.72 -1.6 2,019,735 + RR42_RS29645 0.78 +0.4 2,019,736 - RR42_RS29645 0.78 -0.5 2,019,736 - RR42_RS29645 0.78 +1.0 2,019,736 - RR42_RS29645 0.78 +1.4 2,019,777 + RR42_RS29645 0.85 -0.2 2,019,777 + RR42_RS29645 0.85 -0.8 2,019,777 + RR42_RS29645 0.85 -0.6 2,019,778 - RR42_RS29645 0.85 +0.3 2,019,778 - RR42_RS29645 0.85 -0.5 2,019,796 - RR42_RS29645 0.88 -0.1 2,019,796 - RR42_RS29645 0.88 +0.2 2,019,817 + +0.7 2,019,817 + -1.0 2,019,818 - +1.5 2,019,818 - -0.3 2,019,838 + -0.3 2,019,838 + +1.1 2,019,856 + -1.2 2,019,857 - +0.5 2,019,857 - +0.5 2,019,857 - +2.5 2,019,857 - -0.6 2,019,862 - -1.5 2,019,862 - -0.8 2,019,938 + -1.0 2,019,939 - -1.8 2,019,939 - -0.4 2,019,939 - +0.4 2,019,973 + +2.3 2,019,974 - +1.0 2,019,974 - -0.4 2,019,977 + +0.1 2,019,977 + -0.9 2,019,977 + -0.2 2,019,978 - -0.2 2,019,978 - -0.8 2,019,978 - -0.2 2,019,978 - -0.7 2,019,978 - -0.8 2,019,978 - -1.9 2,019,985 - -1.0 2,020,000 + +0.0 2,020,014 + -0.3 2,020,015 - +0.4 2,020,015 - -1.5 2,020,103 + -0.8 2,020,104 - -1.0 2,020,104 - -1.1 2,020,154 - -1.0 2,020,154 - +0.8 2,020,172 + +0.7 2,020,172 + -1.0 2,020,188 + +0.1 2,020,194 + +1.5 2,020,195 - +0.1 2,020,293 + RR42_RS29650 0.22 -0.3 2,020,294 - RR42_RS29650 0.22 +0.4 2,020,294 - RR42_RS29650 0.22 -1.2 2,020,294 - RR42_RS29650 0.22 -1.0 2,020,294 - RR42_RS29650 0.22 -2.5 2,020,294 - RR42_RS29650 0.22 -1.2 2,020,300 + RR42_RS29650 0.23 -0.6 2,020,301 - RR42_RS29650 0.23 -0.5 2,020,301 - RR42_RS29650 0.23 +0.0 2,020,311 + RR42_RS29650 0.24 -0.3 2,020,337 + RR42_RS29650 0.28 -1.3 2,020,337 + RR42_RS29650 0.28 -0.1 2,020,337 + RR42_RS29650 0.28 -1.5 2,020,439 + RR42_RS29650 0.43 -1.3 2,020,465 + RR42_RS29650 0.47 +1.0 2,020,466 - RR42_RS29650 0.47 +1.2 2,020,466 - RR42_RS29650 0.47 -0.6 2,020,470 + RR42_RS29650 0.47 -2.7 2,020,470 + RR42_RS29650 0.47 -0.0 2,020,470 + RR42_RS29650 0.47 -1.8 2,020,534 + RR42_RS29650 0.57 -1.0 2,020,535 - RR42_RS29650 0.57 -1.8 2,020,556 + RR42_RS29650 0.60 -2.9 2,020,557 - RR42_RS29650 0.60 -1.1 2,020,748 - RR42_RS29650 0.88 +0.6 2,020,748 - RR42_RS29650 0.88 -0.3 2,020,756 - RR42_RS29650 0.89 -0.7 2,020,801 + -1.3 2,020,801 + +0.2 2,020,802 - +0.2 2,020,802 - +0.4 2,020,831 + +0.2 2,020,832 - -0.5 2,020,845 + -0.8
Or see this region's nucleotide sequence