Experiment: R2A with Vancomycin 0.5 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt RR42_RS17430 and RR42_RS17435 are separated by 22 nucleotides RR42_RS17435 and RR42_RS17440 are separated by 496 nucleotides
RR42_RS17430: RR42_RS17430 - histidine kinase, at 3,773,254 to 3,774,585
_RS17430
RR42_RS17435: RR42_RS17435 - SAM-dependent methyltransferase, at 3,774,608 to 3,775,999
_RS17435
RR42_RS17440: RR42_RS17440 - polyisoprenoid-binding protein, at 3,776,496 to 3,777,077
_RS17440
Position (kb)
3774
3775
3776 Strain fitness (log2 ratio)
-2
-1
0
1
2
3
4
5 at 3774.059 kb on + strand, within RR42_RS17430 at 3774.059 kb on + strand, within RR42_RS17430 at 3774.060 kb on - strand, within RR42_RS17430 at 3774.060 kb on - strand, within RR42_RS17430 at 3774.060 kb on - strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.063 kb on + strand, within RR42_RS17430 at 3774.064 kb on - strand, within RR42_RS17430 at 3774.064 kb on - strand, within RR42_RS17430 at 3774.064 kb on - strand, within RR42_RS17430 at 3774.064 kb on - strand, within RR42_RS17430 at 3774.064 kb on - strand, within RR42_RS17430 at 3774.064 kb on - strand, within RR42_RS17430 at 3774.065 kb on + strand, within RR42_RS17430 at 3774.065 kb on + strand, within RR42_RS17430 at 3774.065 kb on + strand, within RR42_RS17430 at 3774.065 kb on + strand, within RR42_RS17430 at 3774.065 kb on + strand, within RR42_RS17430 at 3774.065 kb on + strand, within RR42_RS17430 at 3774.066 kb on - strand, within RR42_RS17430 at 3774.066 kb on - strand, within RR42_RS17430 at 3774.066 kb on - strand, within RR42_RS17430 at 3774.066 kb on - strand, within RR42_RS17430 at 3774.066 kb on - strand, within RR42_RS17430 at 3774.066 kb on - strand, within RR42_RS17430 at 3774.067 kb on + strand, within RR42_RS17430 at 3774.067 kb on + strand, within RR42_RS17430 at 3774.067 kb on + strand, within RR42_RS17430 at 3774.067 kb on + strand, within RR42_RS17430 at 3774.067 kb on + strand, within RR42_RS17430 at 3774.067 kb on + strand, within RR42_RS17430 at 3774.067 kb on + strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.068 kb on - strand, within RR42_RS17430 at 3774.114 kb on + strand, within RR42_RS17430 at 3774.114 kb on + strand, within RR42_RS17430 at 3774.167 kb on + strand, within RR42_RS17430 at 3774.167 kb on + strand, within RR42_RS17430 at 3774.168 kb on - strand, within RR42_RS17430 at 3774.176 kb on + strand, within RR42_RS17430 at 3774.176 kb on + strand, within RR42_RS17430 at 3774.176 kb on + strand, within RR42_RS17430 at 3774.176 kb on + strand, within RR42_RS17430 at 3774.177 kb on - strand, within RR42_RS17430 at 3774.263 kb on + strand, within RR42_RS17430 at 3774.264 kb on - strand, within RR42_RS17430 at 3774.264 kb on - strand, within RR42_RS17430 at 3774.264 kb on - strand, within RR42_RS17430 at 3774.267 kb on - strand, within RR42_RS17430 at 3774.288 kb on + strand, within RR42_RS17430 at 3774.378 kb on - strand, within RR42_RS17430 at 3774.378 kb on - strand, within RR42_RS17430 at 3774.378 kb on - strand, within RR42_RS17430 at 3774.378 kb on - strand, within RR42_RS17430 at 3774.378 kb on - strand, within RR42_RS17430 at 3774.464 kb on + strand at 3774.465 kb on - strand at 3774.465 kb on - strand at 3774.504 kb on + strand at 3774.505 kb on - strand at 3774.506 kb on + strand at 3774.506 kb on + strand at 3774.507 kb on - strand at 3774.507 kb on - strand at 3774.507 kb on - strand at 3774.507 kb on - strand at 3774.507 kb on - strand at 3774.657 kb on + strand at 3774.657 kb on + strand at 3774.657 kb on + strand at 3774.657 kb on + strand at 3774.658 kb on - strand at 3774.658 kb on - strand at 3774.658 kb on - strand at 3774.658 kb on - strand at 3774.658 kb on - strand at 3774.694 kb on + strand at 3774.695 kb on - strand at 3774.695 kb on - strand at 3774.695 kb on - strand at 3774.695 kb on - strand at 3774.717 kb on + strand at 3774.718 kb on - strand at 3774.726 kb on + strand at 3774.785 kb on + strand, within RR42_RS17435 at 3774.825 kb on + strand, within RR42_RS17435 at 3774.825 kb on + strand, within RR42_RS17435 at 3774.862 kb on - strand, within RR42_RS17435 at 3774.862 kb on - strand, within RR42_RS17435 at 3774.862 kb on - strand, within RR42_RS17435 at 3774.882 kb on + strand, within RR42_RS17435 at 3774.882 kb on + strand, within RR42_RS17435 at 3774.883 kb on - strand, within RR42_RS17435 at 3775.023 kb on + strand, within RR42_RS17435 at 3775.024 kb on - strand, within RR42_RS17435 at 3775.024 kb on - strand, within RR42_RS17435 at 3775.024 kb on - strand, within RR42_RS17435 at 3775.067 kb on + strand, within RR42_RS17435 at 3775.067 kb on + strand, within RR42_RS17435 at 3775.067 kb on + strand, within RR42_RS17435 at 3775.068 kb on - strand, within RR42_RS17435 at 3775.068 kb on - strand, within RR42_RS17435 at 3775.068 kb on - strand, within RR42_RS17435 at 3775.252 kb on + strand, within RR42_RS17435 at 3775.252 kb on + strand, within RR42_RS17435 at 3775.253 kb on - strand, within RR42_RS17435 at 3775.269 kb on + strand, within RR42_RS17435 at 3775.320 kb on + strand, within RR42_RS17435 at 3775.321 kb on - strand, within RR42_RS17435 at 3775.321 kb on - strand, within RR42_RS17435 at 3775.407 kb on + strand, within RR42_RS17435 at 3775.408 kb on - strand, within RR42_RS17435 at 3775.473 kb on + strand, within RR42_RS17435 at 3775.473 kb on + strand, within RR42_RS17435 at 3775.474 kb on - strand, within RR42_RS17435 at 3775.512 kb on + strand, within RR42_RS17435 at 3775.512 kb on + strand, within RR42_RS17435 at 3775.513 kb on - strand, within RR42_RS17435 at 3775.633 kb on - strand, within RR42_RS17435 at 3775.646 kb on - strand, within RR42_RS17435 at 3775.813 kb on - strand, within RR42_RS17435 at 3775.879 kb on - strand at 3775.887 kb on + strand at 3775.924 kb on + strand at 3775.924 kb on + strand at 3775.924 kb on + strand at 3775.925 kb on - strand at 3775.967 kb on - strand at 3775.995 kb on + strand at 3775.995 kb on + strand at 3775.995 kb on + strand at 3775.996 kb on - strand at 3775.996 kb on - strand at 3776.002 kb on + strand at 3776.081 kb on + strand at 3776.097 kb on + strand at 3776.102 kb on + strand at 3776.110 kb on + strand at 3776.110 kb on + strand at 3776.111 kb on - strand at 3776.120 kb on + strand at 3776.120 kb on + strand at 3776.131 kb on + strand at 3776.131 kb on + strand at 3776.131 kb on + strand at 3776.131 kb on + strand at 3776.131 kb on + strand at 3776.131 kb on + strand at 3776.132 kb on - strand at 3776.132 kb on - strand at 3776.132 kb on - strand at 3776.188 kb on - strand at 3776.197 kb on + strand at 3776.197 kb on + strand at 3776.198 kb on - strand at 3776.233 kb on + strand at 3776.233 kb on + strand at 3776.241 kb on + strand at 3776.248 kb on + strand at 3776.256 kb on + strand at 3776.256 kb on + strand at 3776.257 kb on - strand at 3776.257 kb on - strand at 3776.280 kb on + strand at 3776.280 kb on + strand at 3776.280 kb on + strand at 3776.280 kb on + strand at 3776.280 kb on + strand at 3776.280 kb on + strand at 3776.280 kb on + strand at 3776.281 kb on - strand at 3776.281 kb on - strand at 3776.281 kb on - strand at 3776.307 kb on + strand at 3776.307 kb on + strand at 3776.308 kb on - strand at 3776.497 kb on + strand at 3776.508 kb on + strand at 3776.509 kb on - strand at 3776.566 kb on + strand, within RR42_RS17440 at 3776.567 kb on - strand, within RR42_RS17440 at 3776.761 kb on + strand, within RR42_RS17440 at 3776.761 kb on + strand, within RR42_RS17440 at 3776.761 kb on + strand, within RR42_RS17440 at 3776.761 kb on + strand, within RR42_RS17440 at 3776.761 kb on + strand, within RR42_RS17440 at 3776.761 kb on + strand, within RR42_RS17440 at 3776.761 kb on + strand, within RR42_RS17440 at 3776.761 kb on + strand, within RR42_RS17440 at 3776.761 kb on + strand, within RR42_RS17440 at 3776.762 kb on - strand, within RR42_RS17440 at 3776.762 kb on - strand, within RR42_RS17440 at 3776.762 kb on - strand, within RR42_RS17440
Per-strain Table
Position Strand Gene LocusTag Fraction R2A with Vancomycin 0.5 mg/ml remove 3,774,059 + RR42_RS17430 0.60 +0.4 3,774,059 + RR42_RS17430 0.60 +1.0 3,774,060 - RR42_RS17430 0.61 -0.4 3,774,060 - RR42_RS17430 0.61 -2.4 3,774,060 - RR42_RS17430 0.61 +1.6 3,774,063 + RR42_RS17430 0.61 -0.8 3,774,063 + RR42_RS17430 0.61 +0.2 3,774,063 + RR42_RS17430 0.61 +1.3 3,774,063 + RR42_RS17430 0.61 +0.6 3,774,063 + RR42_RS17430 0.61 +0.1 3,774,063 + RR42_RS17430 0.61 +0.1 3,774,063 + RR42_RS17430 0.61 +0.7 3,774,063 + RR42_RS17430 0.61 -0.6 3,774,063 + RR42_RS17430 0.61 +0.8 3,774,063 + RR42_RS17430 0.61 +1.0 3,774,063 + RR42_RS17430 0.61 +0.3 3,774,063 + RR42_RS17430 0.61 +0.4 3,774,063 + RR42_RS17430 0.61 +0.3 3,774,063 + RR42_RS17430 0.61 +0.2 3,774,064 - RR42_RS17430 0.61 -1.0 3,774,064 - RR42_RS17430 0.61 -0.7 3,774,064 - RR42_RS17430 0.61 +1.6 3,774,064 - RR42_RS17430 0.61 +0.3 3,774,064 - RR42_RS17430 0.61 +0.1 3,774,064 - RR42_RS17430 0.61 +0.6 3,774,065 + RR42_RS17430 0.61 +0.1 3,774,065 + RR42_RS17430 0.61 +0.2 3,774,065 + RR42_RS17430 0.61 -0.1 3,774,065 + RR42_RS17430 0.61 +0.3 3,774,065 + RR42_RS17430 0.61 +0.6 3,774,065 + RR42_RS17430 0.61 +2.0 3,774,066 - RR42_RS17430 0.61 -0.0 3,774,066 - RR42_RS17430 0.61 +0.4 3,774,066 - RR42_RS17430 0.61 +0.1 3,774,066 - RR42_RS17430 0.61 -1.8 3,774,066 - RR42_RS17430 0.61 -1.1 3,774,066 - RR42_RS17430 0.61 +0.7 3,774,067 + RR42_RS17430 0.61 +0.2 3,774,067 + RR42_RS17430 0.61 -0.3 3,774,067 + RR42_RS17430 0.61 +0.9 3,774,067 + RR42_RS17430 0.61 +0.1 3,774,067 + RR42_RS17430 0.61 -0.4 3,774,067 + RR42_RS17430 0.61 -0.1 3,774,067 + RR42_RS17430 0.61 +0.4 3,774,068 - RR42_RS17430 0.61 +1.6 3,774,068 - RR42_RS17430 0.61 +1.0 3,774,068 - RR42_RS17430 0.61 -1.0 3,774,068 - RR42_RS17430 0.61 -2.0 3,774,068 - RR42_RS17430 0.61 -0.8 3,774,068 - RR42_RS17430 0.61 +1.0 3,774,068 - RR42_RS17430 0.61 +0.1 3,774,068 - RR42_RS17430 0.61 +0.3 3,774,068 - RR42_RS17430 0.61 -0.2 3,774,068 - RR42_RS17430 0.61 +0.3 3,774,068 - RR42_RS17430 0.61 +0.8 3,774,068 - RR42_RS17430 0.61 -0.2 3,774,114 + RR42_RS17430 0.65 +0.8 3,774,114 + RR42_RS17430 0.65 +0.8 3,774,167 + RR42_RS17430 0.69 +1.6 3,774,167 + RR42_RS17430 0.69 +0.7 3,774,168 - RR42_RS17430 0.69 +0.5 3,774,176 + RR42_RS17430 0.69 +1.5 3,774,176 + RR42_RS17430 0.69 +1.6 3,774,176 + RR42_RS17430 0.69 -0.8 3,774,176 + RR42_RS17430 0.69 +0.0 3,774,177 - RR42_RS17430 0.69 -1.4 3,774,263 + RR42_RS17430 0.76 -0.3 3,774,264 - RR42_RS17430 0.76 +1.4 3,774,264 - RR42_RS17430 0.76 -0.1 3,774,264 - RR42_RS17430 0.76 -0.5 3,774,267 - RR42_RS17430 0.76 +2.3 3,774,288 + RR42_RS17430 0.78 -1.8 3,774,378 - RR42_RS17430 0.84 +2.0 3,774,378 - RR42_RS17430 0.84 +3.2 3,774,378 - RR42_RS17430 0.84 +1.1 3,774,378 - RR42_RS17430 0.84 +0.9 3,774,378 - RR42_RS17430 0.84 +4.8 3,774,464 + -2.3 3,774,465 - +1.1 3,774,465 - +1.6 3,774,504 + -1.8 3,774,505 - +2.0 3,774,506 + +1.9 3,774,506 + +2.3 3,774,507 - +1.7 3,774,507 - +3.4 3,774,507 - +1.4 3,774,507 - +1.5 3,774,507 - +1.0 3,774,657 + +1.0 3,774,657 + +0.6 3,774,657 + +0.3 3,774,657 + -1.2 3,774,658 - +0.4 3,774,658 - +1.2 3,774,658 - +0.5 3,774,658 - +0.3 3,774,658 - +0.5 3,774,694 + +0.4 3,774,695 - -0.0 3,774,695 - -0.7 3,774,695 - -0.5 3,774,695 - +1.4 3,774,717 + +0.3 3,774,718 - +0.7 3,774,726 + +1.6 3,774,785 + RR42_RS17435 0.13 +0.5 3,774,825 + RR42_RS17435 0.16 -0.7 3,774,825 + RR42_RS17435 0.16 +0.3 3,774,862 - RR42_RS17435 0.18 +0.3 3,774,862 - RR42_RS17435 0.18 -0.7 3,774,862 - RR42_RS17435 0.18 +1.9 3,774,882 + RR42_RS17435 0.20 +1.0 3,774,882 + RR42_RS17435 0.20 -0.2 3,774,883 - RR42_RS17435 0.20 -0.8 3,775,023 + RR42_RS17435 0.30 +0.2 3,775,024 - RR42_RS17435 0.30 +0.9 3,775,024 - RR42_RS17435 0.30 +0.0 3,775,024 - RR42_RS17435 0.30 -0.4 3,775,067 + RR42_RS17435 0.33 -0.2 3,775,067 + RR42_RS17435 0.33 -0.1 3,775,067 + RR42_RS17435 0.33 +1.1 3,775,068 - RR42_RS17435 0.33 -0.2 3,775,068 - RR42_RS17435 0.33 -0.4 3,775,068 - RR42_RS17435 0.33 +1.5 3,775,252 + RR42_RS17435 0.46 +0.8 3,775,252 + RR42_RS17435 0.46 +0.4 3,775,253 - RR42_RS17435 0.46 +0.4 3,775,269 + RR42_RS17435 0.47 +2.6 3,775,320 + RR42_RS17435 0.51 +0.6 3,775,321 - RR42_RS17435 0.51 -0.7 3,775,321 - RR42_RS17435 0.51 +0.8 3,775,407 + RR42_RS17435 0.57 +0.3 3,775,408 - RR42_RS17435 0.57 -0.3 3,775,473 + RR42_RS17435 0.62 +0.9 3,775,473 + RR42_RS17435 0.62 +0.1 3,775,474 - RR42_RS17435 0.62 -1.7 3,775,512 + RR42_RS17435 0.65 +0.2 3,775,512 + RR42_RS17435 0.65 -0.7 3,775,513 - RR42_RS17435 0.65 -0.3 3,775,633 - RR42_RS17435 0.74 -0.0 3,775,646 - RR42_RS17435 0.75 -0.3 3,775,813 - RR42_RS17435 0.87 -0.8 3,775,879 - -0.6 3,775,887 + +0.3 3,775,924 + -0.4 3,775,924 + +0.6 3,775,924 + +0.2 3,775,925 - -0.4 3,775,967 - +0.1 3,775,995 + +0.5 3,775,995 + -0.4 3,775,995 + +1.0 3,775,996 - +0.2 3,775,996 - -1.5 3,776,002 + +0.8 3,776,081 + +0.4 3,776,097 + +1.0 3,776,102 + +0.2 3,776,110 + -1.0 3,776,110 + +0.2 3,776,111 - -0.2 3,776,120 + +0.3 3,776,120 + +0.7 3,776,131 + +0.4 3,776,131 + +0.6 3,776,131 + -0.5 3,776,131 + +0.5 3,776,131 + -2.0 3,776,131 + +0.3 3,776,132 - +2.6 3,776,132 - -1.1 3,776,132 - +0.3 3,776,188 - -0.1 3,776,197 + +0.1 3,776,197 + +0.1 3,776,198 - -1.1 3,776,233 + +0.0 3,776,233 + +0.0 3,776,241 + +0.6 3,776,248 + +0.1 3,776,256 + -1.0 3,776,256 + -0.0 3,776,257 - +0.4 3,776,257 - -2.6 3,776,280 + +0.2 3,776,280 + -0.8 3,776,280 + +3.6 3,776,280 + -0.2 3,776,280 + +0.9 3,776,280 + -1.6 3,776,280 + +0.2 3,776,281 - -0.7 3,776,281 - -0.3 3,776,281 - +0.9 3,776,307 + -0.2 3,776,307 + +1.2 3,776,308 - +0.6 3,776,497 + -0.8 3,776,508 + -1.2 3,776,509 - -0.0 3,776,566 + RR42_RS17440 0.12 -0.0 3,776,567 - RR42_RS17440 0.12 +1.2 3,776,761 + RR42_RS17440 0.46 +0.4 3,776,761 + RR42_RS17440 0.46 +0.9 3,776,761 + RR42_RS17440 0.46 -0.2 3,776,761 + RR42_RS17440 0.46 +0.2 3,776,761 + RR42_RS17440 0.46 -0.1 3,776,761 + RR42_RS17440 0.46 -0.1 3,776,761 + RR42_RS17440 0.46 +2.8 3,776,761 + RR42_RS17440 0.46 +1.8 3,776,761 + RR42_RS17440 0.46 +0.8 3,776,762 - RR42_RS17440 0.46 +1.1 3,776,762 - RR42_RS17440 0.46 +0.4 3,776,762 - RR42_RS17440 0.46 -0.3
Or see this region's nucleotide sequence