Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3575c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
4,016,101	-				-0.1
4,016,242	+				-0.8
4,016,243	-				-0.9
4,016,243	-				-1.0
4,016,282	-				-0.3
4,016,315	+				-1.4
4,016,316	-				-0.1
4,016,316	-				-0.4
4,016,316	-				+1.3
4,016,362	+				-0.3
4,016,362	+				-1.1
4,016,363	-				-0.0
4,016,418	+				+0.0
4,016,447	+				-0.6
4,016,492	-				+2.0
4,016,644	-		Rv3574	0.27	-0.5
4,016,835	+		Rv3574	0.58	+0.9
4,017,082	-				-0.1
4,017,179	+				+1.0
4,017,295	-		Rv3575c	0.19	-0.5
4,017,316	-		Rv3575c	0.21	-0.4
4,017,430	-		Rv3575c	0.32	-0.1
4,017,489	-		Rv3575c	0.37	-0.5
4,017,513	-		Rv3575c	0.39	-1.0
4,017,513	-		Rv3575c	0.39	-0.2
4,017,624	+		Rv3575c	0.50	-0.4
4,017,744	+		Rv3575c	0.61	-0.5
4,017,769	-		Rv3575c	0.63	-0.0
4,017,931	-		Rv3575c	0.78	+0.2
4,018,014	+		Rv3575c	0.86	+0.2
4,018,052	+		Rv3575c	0.89	-0.4
4,018,172	-				+0.8
4,018,206	-				+0.2
4,018,322	+				-0.6
4,018,322	+				-0.4
4,018,323	-				+0.7
4,018,787	+		Rv3576	0.60	-1.4
4,018,788	-		Rv3576	0.60	-0.5
4,018,909	+		Rv3576	0.77	-0.1
4,018,982	-		Rv3576	0.87	-0.3
4,019,006	-				+0.2
4,019,117	+				-0.2
4,019,117	+				+0.0