Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3272

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
3,652,517	-				-0.9
3,652,530	+				-0.1
3,653,640	+		Rv3272	0.16	-0.4
3,653,686	+		Rv3272	0.20	-0.8
3,653,687	-		Rv3272	0.20	-1.2
3,653,826	+		Rv3272	0.32	-1.1
3,653,826	+		Rv3272	0.32	-0.5
3,653,827	-		Rv3272	0.32	-0.7
3,653,844	+		Rv3272	0.33	-0.7
3,654,086	-		Rv3272	0.54	-0.6
3,654,086	-		Rv3272	0.54	-1.0
3,654,243	+		Rv3272	0.67	+1.2
3,654,243	+		Rv3272	0.67	+0.3
3,654,243	+		Rv3272	0.67	+0.1
3,654,274	-		Rv3272	0.70	-0.9
3,654,274	-		Rv3272	0.70	-0.2
3,654,274	-		Rv3272	0.70	-1.2
3,654,274	-		Rv3272	0.70	-1.1
3,654,342	+		Rv3272	0.75	-0.7
3,654,446	+		Rv3272	0.84	+0.0
3,654,447	-		Rv3272	0.84	-1.1
3,654,447	-		Rv3272	0.84	-0.7
3,655,116	+		Rv3273	0.21	-0.9
3,655,116	+		Rv3273	0.21	-1.2
3,655,149	-		Rv3273	0.22	-0.6
3,655,255	-		Rv3273	0.27	-1.4
3,655,316	+		Rv3273	0.30	-0.6
3,655,317	-		Rv3273	0.30	-0.5