Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3068c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
3,431,049	+		Rv3066	0.56	-0.4
3,431,049	+		Rv3066	0.56	-0.2
3,431,049	+		Rv3066	0.56	+0.2
3,431,050	-		Rv3066	0.56	+1.4
3,431,050	-		Rv3066	0.56	+0.9
3,431,050	-		Rv3066	0.56	-0.1
3,431,180	+		Rv3066	0.78	+1.1
3,431,181	-		Rv3066	0.78	+0.1
3,431,371	+				+0.0
3,431,372	-				-1.5
3,431,378	+				-0.6
3,431,389	+				+0.2
3,431,390	-				-0.7
3,431,390	-				-1.8
3,431,540	+		Rv3067	0.27	-0.3
3,431,739	+		Rv3067	0.76	-0.4
3,431,740	-		Rv3067	0.76	-0.1
3,431,797	+		Rv3067	0.90	-0.6
3,431,810	-				-0.1
3,432,061	+				-0.0
3,432,061	+				+0.1
3,432,070	+				-1.3
3,432,070	+				-0.6
3,432,071	-				+0.5
3,432,071	-				+0.2
3,432,280	+		Rv3068c	0.18	-0.5
3,432,280	+		Rv3068c	0.18	-0.6
3,432,281	-		Rv3068c	0.18	-1.2
3,432,316	+		Rv3068c	0.20	-1.5
3,432,403	-		Rv3068c	0.26	-0.5
3,432,507	+		Rv3068c	0.32	-0.0
3,432,616	+		Rv3068c	0.39	+0.0
3,432,622	+		Rv3068c	0.39	-0.2
3,432,623	-		Rv3068c	0.39	-0.5
3,432,644	-		Rv3068c	0.40	-0.4
3,432,681	+		Rv3068c	0.43	-1.3
3,432,682	-		Rv3068c	0.43	-0.1
3,432,682	-		Rv3068c	0.43	-0.0
3,432,870	+		Rv3068c	0.54	-1.9
3,432,871	-		Rv3068c	0.54	+0.6
3,432,997	+		Rv3068c	0.62	-0.3
3,432,997	+		Rv3068c	0.62	-0.4
3,432,998	-		Rv3068c	0.62	-0.2
3,433,009	+		Rv3068c	0.63	-1.2
3,433,150	+		Rv3068c	0.71	+0.3
3,433,150	+		Rv3068c	0.71	-0.5
3,433,235	-		Rv3068c	0.76	+0.9
3,433,235	-		Rv3068c	0.76	+0.1
3,433,274	-		Rv3068c	0.79	-0.2
3,433,321	-		Rv3068c	0.82	+0.3
3,433,321	-		Rv3068c	0.82	+0.3
3,433,412	-		Rv3068c	0.87	-0.3
3,433,412	-		Rv3068c	0.87	+2.7
3,433,442	+		Rv3068c	0.89	+0.9
3,433,442	+		Rv3068c	0.89	-0.1
3,433,443	-		Rv3068c	0.89	+0.2
3,433,443	-		Rv3068c	0.89	+0.0
3,433,446	+		Rv3068c	0.89	+0.2
3,433,546	+				-1.5
3,433,547	-				-0.1
3,433,668	+				+0.9
3,433,669	-				-0.3
3,433,669	-				-0.6
3,433,669	-				+0.6
3,433,852	-		Rv3069	0.40	-0.3
3,433,894	-		Rv3069	0.51	-1.1
3,434,081	-				-0.3
3,434,295	+		Rv3070	0.55	-0.4
3,434,350	-		Rv3070	0.69	-0.3
3,434,350	-		Rv3070	0.69	+0.3
3,434,350	-		Rv3070	0.69	-0.7
3,434,401	+		Rv3070	0.82	-1.4