Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3006

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
3,363,766	-				+0.9
3,363,780	-		Rv3005c	0.10	+0.0
3,363,780	-		Rv3005c	0.10	-0.1
3,363,878	-		Rv3005c	0.22	-1.0
3,363,878	-		Rv3005c	0.22	-2.3
3,363,901	+		Rv3005c	0.25	-1.1
3,363,901	+		Rv3005c	0.25	-1.2
3,363,901	+		Rv3005c	0.25	-0.5
3,364,045	+		Rv3005c	0.42	-0.5
3,364,045	+		Rv3005c	0.42	-0.9
3,364,045	+		Rv3005c	0.42	-1.3
3,364,046	-		Rv3005c	0.42	-0.9
3,364,046	-		Rv3005c	0.42	-1.3
3,364,069	+		Rv3005c	0.45	+0.9
3,364,070	-		Rv3005c	0.45	-2.0
3,364,183	-		Rv3005c	0.58	-1.5
3,364,300	+		Rv3005c	0.72	-1.6
3,364,300	+		Rv3005c	0.72	-1.6
3,364,301	-		Rv3005c	0.72	-1.4
3,364,301	-		Rv3005c	0.72	-0.9
3,364,333	+		Rv3005c	0.76	-2.6
3,364,358	+		Rv3005c	0.79	-2.8
3,364,359	-		Rv3005c	0.79	-0.7
3,364,369	+		Rv3005c	0.80	-1.6
3,364,369	+		Rv3005c	0.80	-0.7
3,364,369	+		Rv3005c	0.80	-0.1
3,364,369	+		Rv3005c	0.80	-1.2
3,364,370	-		Rv3005c	0.81	+0.5
3,364,380	-		Rv3005c	0.82	-1.5
3,364,414	+		Rv3005c	0.86	-1.0
3,364,414	+		Rv3005c	0.86	+0.1
3,364,415	-		Rv3005c	0.86	-1.6
3,364,415	-		Rv3005c	0.86	-1.5
3,365,969	+		Rv3007c	0.22	+0.2
3,366,032	+		Rv3007c	0.32	+0.4
3,366,032	+		Rv3007c	0.32	+0.6
3,366,033	-		Rv3007c	0.32	-1.6
3,366,276	+		Rv3007c	0.72	-0.4
3,366,277	-		Rv3007c	0.72	-0.1
3,366,484	-				-0.2
3,366,484	-				+0.2
3,366,666	+				-0.1
3,366,666	+				-0.5
3,366,666	+				+0.3
3,366,667	-				+0.1
3,366,667	-				+1.0
3,366,672	+				+0.1
3,366,673	-				+1.9
3,366,673	-				+0.6
3,366,688	-				-0.4
3,366,688	-				-1.9
3,366,694	-				-0.4
3,366,694	-				+1.5
3,366,719	+		Rv3008	0.12	+0.9
3,366,738	+		Rv3008	0.15	-0.9