Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1860

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
2,106,737	+		Rv1859	0.15	-0.1
2,106,737	+		Rv1859	0.15	-0.4
2,106,737	+		Rv1859	0.15	-1.6
2,106,737	+		Rv1859	0.15	+0.2
2,106,738	-		Rv1859	0.15	-0.1
2,106,738	-		Rv1859	0.15	+0.2
2,106,975	+		Rv1859	0.36	-0.2
2,106,976	-		Rv1859	0.36	+0.3
2,106,989	+		Rv1859	0.37	-0.2
2,106,989	+		Rv1859	0.37	+0.1
2,106,990	-		Rv1859	0.37	-0.7
2,106,990	-		Rv1859	0.37	-0.3
2,107,119	+		Rv1859	0.49	-0.9
2,107,119	+		Rv1859	0.49	+0.9
2,107,119	+		Rv1859	0.49	+0.0
2,107,119	+		Rv1859	0.49	+0.4
2,107,120	-		Rv1859	0.49	-0.2
2,107,120	-		Rv1859	0.49	+0.3
2,107,148	+		Rv1859	0.52	-1.8
2,107,149	-		Rv1859	0.52	+0.9
2,107,254	+		Rv1859	0.61	-0.1
2,107,361	-		Rv1859	0.71	-1.5
2,107,436	-		Rv1859	0.78	-0.2
2,107,467	+		Rv1859	0.80	+0.0
2,107,467	+		Rv1859	0.80	-0.1
2,107,723	+				+0.3
2,107,723	+				-0.7
2,107,723	+				+0.3
2,107,724	-				+1.3
2,107,724	-				+2.9
2,108,324	+		Rv1860	0.60	-0.6
2,108,324	+		Rv1860	0.60	-0.8
2,108,324	+		Rv1860	0.60	-2.6
2,108,325	-		Rv1860	0.60	-2.6
2,108,325	-		Rv1860	0.60	-0.7
2,108,325	-		Rv1860	0.60	-0.3
2,108,325	-		Rv1860	0.60	-1.2
2,108,326	+		Rv1860	0.60	-1.4
2,108,405	+		Rv1860	0.68	+0.5
2,108,461	-		Rv1860	0.74	-2.1
2,108,520	+		Rv1860	0.80	-1.7
2,108,704	-				-0.4
2,108,907	-				-1.3
2,109,109	+				+0.0
2,109,111	+				+0.5
2,109,112	-				-0.9
2,109,117	+				+0.1
2,109,222	-		Rv1861	0.19	+0.1
2,109,223	+		Rv1861	0.19	-1.5
2,109,224	-		Rv1861	0.19	+0.1
2,109,224	-		Rv1861	0.19	-0.4
2,109,224	-		Rv1861	0.19	-0.4
2,109,224	-		Rv1861	0.19	+0.6
2,109,237	+		Rv1861	0.24	-0.4
2,109,237	+		Rv1861	0.24	-0.4
2,109,238	-		Rv1861	0.24	+0.0
2,109,238	-		Rv1861	0.24	+0.8
2,109,254	+		Rv1861	0.29	+0.6
2,109,394	-		Rv1861	0.75	+0.0