Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3897c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3896c and Rv3897c are separated by 156 nucleotidesRv3897c and Rv3898c are separated by 12 nucleotidesRv3898c and Rv3899c are separated by 161 nucleotides Rv3896c: Rv3896c - Conserved hypothetical protein, at 4,381,943 to 4,382,851 Rv3896c Rv3897c: Rv3897c - Conserved hypothetical protein, at 4,383,008 to 4,383,640 Rv3897c Rv3898c: Rv3898c - Conserved hypothetical protein, at 4,383,653 to 4,383,985 Rv3898c Rv3899c: Rv3899c - Conserved hypothetical protein, at 4,384,147 to 4,385,379 Rv3899c Position (kb) 4383 4384Strain fitness (log2 ratio) -2 -1 0 1 2 3at 4382.037 kb on + strand, within Rv3896cat 4382.037 kb on + strand, within Rv3896cat 4382.037 kb on + strand, within Rv3896cat 4382.103 kb on + strand, within Rv3896cat 4382.183 kb on + strand, within Rv3896cat 4382.199 kb on + strand, within Rv3896cat 4382.334 kb on - strand, within Rv3896cat 4382.334 kb on - strand, within Rv3896cat 4382.413 kb on + strand, within Rv3896cat 4382.413 kb on + strand, within Rv3896cat 4382.653 kb on - strand, within Rv3896cat 4382.653 kb on - strand, within Rv3896cat 4382.937 kb on + strandat 4382.937 kb on + strandat 4382.937 kb on + strandat 4382.938 kb on - strandat 4382.938 kb on - strandat 4383.002 kb on + strandat 4383.010 kb on - strandat 4383.175 kb on + strand, within Rv3897cat 4383.492 kb on + strand, within Rv3897cat 4383.755 kb on + strand, within Rv3898cat 4383.755 kb on + strand, within Rv3898cat 4383.755 kb on + strand, within Rv3898cat 4383.756 kb on - strand, within Rv3898cat 4383.756 kb on - strand, within Rv3898cat 4383.802 kb on + strand, within Rv3898cat 4383.848 kb on + strand, within Rv3898cat 4383.854 kb on + strand, within Rv3898cat 4383.915 kb on - strand, within Rv3898cat 4383.915 kb on - strand, within Rv3898cat 4384.010 kb on - strandat 4384.193 kb on + strandat 4384.193 kb on + strandat 4384.193 kb on + strandat 4384.194 kb on - strandat 4384.194 kb on - strandat 4384.194 kb on - strandat 4384.208 kb on + strandat 4384.208 kb on + strandat 4384.208 kb on + strandat 4384.209 kb on - strandat 4384.209 kb on - strandat 4384.220 kb on + strandat 4384.220 kb on + strandat 4384.298 kb on + strand, within Rv3899cat 4384.298 kb on + strand, within Rv3899cat 4384.422 kb on + strand, within Rv3899cat 4384.541 kb on + strand, within Rv3899cat 4384.541 kb on + strand, within Rv3899cat 4384.541 kb on + strand, within Rv3899cat 4384.541 kb on + strand, within Rv3899cat 4384.541 kb on + strand, within Rv3899cat 4384.542 kb on - strand, within Rv3899cat 4384.542 kb on - strand, within Rv3899cat 4384.542 kb on - strand, within Rv3899cat 4384.542 kb on - strand, within Rv3899cat 4384.542 kb on - strand, within Rv3899cat 4384.542 kb on - strand, within Rv3899c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Clarithromycin 0.967 ug/mL
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4,382,037 + Rv3896c 0.10 -0.3
4,382,037 + Rv3896c 0.10 -0.4
4,382,037 + Rv3896c 0.10 -1.5
4,382,103 + Rv3896c 0.18 +2.5
4,382,183 + Rv3896c 0.26 +0.3
4,382,199 + Rv3896c 0.28 -1.1
4,382,334 - Rv3896c 0.43 -1.6
4,382,334 - Rv3896c 0.43 -0.0
4,382,413 + Rv3896c 0.52 +0.0
4,382,413 + Rv3896c 0.52 -0.5
4,382,653 - Rv3896c 0.78 -1.3
4,382,653 - Rv3896c 0.78 +0.9
4,382,937 + +0.4
4,382,937 + -0.3
4,382,937 + -0.2
4,382,938 - -1.7
4,382,938 - -0.3
4,383,002 + +0.5
4,383,010 - -0.4
4,383,175 + Rv3897c 0.26 +0.5
4,383,492 + Rv3897c 0.76 +0.9
4,383,755 + Rv3898c 0.31 -0.4
4,383,755 + Rv3898c 0.31 +0.4
4,383,755 + Rv3898c 0.31 +0.5
4,383,756 - Rv3898c 0.31 +0.9
4,383,756 - Rv3898c 0.31 +0.6
4,383,802 + Rv3898c 0.45 -0.2
4,383,848 + Rv3898c 0.59 -0.8
4,383,854 + Rv3898c 0.60 -0.1
4,383,915 - Rv3898c 0.79 -0.4
4,383,915 - Rv3898c 0.79 -0.1
4,384,010 - +0.2
4,384,193 + -0.9
4,384,193 + -0.1
4,384,193 + -0.2
4,384,194 - -0.4
4,384,194 - -0.0
4,384,194 - -0.3
4,384,208 + -0.8
4,384,208 + -0.5
4,384,208 + +0.0
4,384,209 - -0.3
4,384,209 - +3.2
4,384,220 + -1.0
4,384,220 + +0.4
4,384,298 + Rv3899c 0.12 +0.1
4,384,298 + Rv3899c 0.12 -0.7
4,384,422 + Rv3899c 0.22 -2.3
4,384,541 + Rv3899c 0.32 +0.6
4,384,541 + Rv3899c 0.32 -0.1
4,384,541 + Rv3899c 0.32 +0.2
4,384,541 + Rv3899c 0.32 -0.1
4,384,541 + Rv3899c 0.32 -0.0
4,384,542 - Rv3899c 0.32 +0.0
4,384,542 - Rv3899c 0.32 -0.5
4,384,542 - Rv3899c 0.32 +0.5
4,384,542 - Rv3899c 0.32 -0.7
4,384,542 - Rv3899c 0.32 -0.0
4,384,542 - Rv3899c 0.32 -0.1

Or see this region's nucleotide sequence