Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3198A

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
3,571,233	-				-0.1
3,571,322	-				+0.9
3,571,359	+				-0.6
3,571,359	+				+0.9
3,571,359	+				-0.2
3,571,360	-				-0.1
3,571,360	-				-0.0
3,571,360	-				-2.3
3,571,360	-				+0.2
3,571,360	-				-0.2
3,571,360	-				+0.1
3,571,360	-				+0.2
3,571,360	-				-0.5
3,571,361	+		Rv3198A	0.10	+0.1
3,571,362	-		Rv3198A	0.11	+0.2
3,571,380	+		Rv3198A	0.18	+1.2
3,571,381	-		Rv3198A	0.18	-0.3
3,571,426	-		Rv3198A	0.36	+1.2
3,571,588	-				-0.0
3,571,850	-		Rv3199c	0.26	+0.9
3,572,115	+		Rv3199c	0.54	-0.2
3,572,235	+		Rv3199c	0.67	+0.9
3,572,235	+		Rv3199c	0.67	-0.2
3,572,236	-		Rv3199c	0.67	+2.5
3,572,236	-		Rv3199c	0.67	+0.3
3,572,236	-		Rv3199c	0.67	+0.3
3,572,313	+		Rv3199c	0.75	-0.4
3,572,313	+		Rv3199c	0.75	-0.2
3,572,533	-				-1.0
3,572,533	-				+0.5
3,572,533	-				-0.6