Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3193c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
3,559,195	-				-1.3
3,559,296	-				+0.1
3,559,533	+				+0.9
3,559,534	-				+0.6
3,559,775	+		Rv3192	0.46	-0.2
3,559,776	-		Rv3192	0.46	-0.2
3,559,837	-		Rv3192	0.59	-0.4
3,559,841	+		Rv3192	0.60	+0.4
3,559,875	+		Rv3192	0.68	+0.2
3,559,876	-		Rv3192	0.68	+0.1
3,560,341	+				-0.3
3,560,615	+		Rv3193c	0.14	+1.3
3,560,940	-		Rv3193c	0.25	+0.7
3,561,612	+		Rv3193c	0.48	+0.3
3,562,204	-		Rv3193c	0.67	+1.9
3,562,479	-		Rv3193c	0.77	-1.4
3,563,266	-				+0.7
3,563,323	+				-2.1
3,563,643	-		Rv3194c	0.37	-0.3
3,563,671	+		Rv3194c	0.40	-0.1
3,563,671	+		Rv3194c	0.40	+0.1
3,563,672	-		Rv3194c	0.40	-1.2
3,563,916	+		Rv3194c	0.64	+0.2
3,563,994	+		Rv3194c	0.71	-0.3
3,564,062	+		Rv3194c	0.78	+0.1
3,564,063	-		Rv3194c	0.78	+0.0
3,564,114	+		Rv3194c	0.83	-0.5
3,564,155	+		Rv3194c	0.87	-0.1