Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2948c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
3,297,039	+		Rv2947c	0.46	+0.1
3,297,039	+		Rv2947c	0.46	+1.0
3,297,040	-		Rv2947c	0.46	-0.4
3,297,040	-		Rv2947c	0.46	-0.1
3,297,202	-		Rv2947c	0.57	+0.4
3,297,235	+		Rv2947c	0.59	+0.8
3,297,240	-		Rv2947c	0.60	-0.4
3,297,240	-		Rv2947c	0.60	-0.4
3,297,240	-		Rv2947c	0.60	-0.0
3,297,240	-		Rv2947c	0.60	-0.7
3,297,240	-		Rv2947c	0.60	-0.9
3,297,288	-		Rv2947c	0.63	+0.1
3,297,312	+		Rv2947c	0.65	-0.2
3,297,313	-		Rv2947c	0.65	-0.4
3,297,313	-		Rv2947c	0.65	-0.2
3,297,344	+		Rv2947c	0.67	-0.9
3,297,459	+		Rv2947c	0.74	+0.7
3,297,460	-		Rv2947c	0.74	-0.3
3,297,527	+		Rv2947c	0.79	+0.3
3,297,560	+		Rv2947c	0.81	+0.7
3,297,560	+		Rv2947c	0.81	-0.2
3,297,561	-		Rv2947c	0.81	-0.2
3,297,561	-		Rv2947c	0.81	-0.2
3,297,561	-		Rv2947c	0.81	-0.7
3,297,562	+		Rv2947c	0.81	-0.1
3,297,562	+		Rv2947c	0.81	+0.3
3,297,563	-		Rv2947c	0.81	-0.2
3,297,720	-				-0.7
3,297,769	+				+0.2
3,297,769	+				-0.1
3,297,769	+				-1.5
3,297,769	+				-0.4
3,297,770	-				-0.8
3,297,770	-				-0.1
3,297,773	+				-0.5
3,297,774	-				+0.8
3,297,835	+				-0.2
3,297,835	+				+0.1
3,297,836	-				+0.3
3,298,115	-		Rv2948c	0.13	-0.3
3,298,142	-		Rv2948c	0.14	-0.3
3,298,281	+		Rv2948c	0.21	-0.0
3,298,281	+		Rv2948c	0.21	-0.2
3,298,281	+		Rv2948c	0.21	-0.2
3,298,281	+		Rv2948c	0.21	+0.0
3,298,281	+		Rv2948c	0.21	+0.1
3,298,281	+		Rv2948c	0.21	+0.0
3,298,282	-		Rv2948c	0.21	+0.9
3,298,282	-		Rv2948c	0.21	+0.2
3,298,282	-		Rv2948c	0.21	-0.1
3,298,305	+		Rv2948c	0.22	-0.3
3,298,808	-		Rv2948c	0.46	+1.3
3,298,808	-		Rv2948c	0.46	-0.4
3,298,811	+		Rv2948c	0.46	+1.3
3,298,811	+		Rv2948c	0.46	+0.0
3,298,812	-		Rv2948c	0.46	+0.2
3,298,812	-		Rv2948c	0.46	-0.6
3,298,832	+		Rv2948c	0.47	+0.3
3,298,929	+		Rv2948c	0.52	+1.0
3,298,929	+		Rv2948c	0.52	+0.1
3,298,930	-		Rv2948c	0.52	-0.4
3,299,070	-		Rv2948c	0.58	+0.2
3,299,365	+		Rv2948c	0.72	+1.6
3,299,378	+		Rv2948c	0.73	-0.7
3,299,382	+		Rv2948c	0.73	-0.0
3,299,417	+		Rv2948c	0.75	+0.8
3,299,426	+		Rv2948c	0.75	+0.1
3,299,426	+		Rv2948c	0.75	-0.1
3,299,427	-		Rv2948c	0.75	-0.4
3,299,427	-		Rv2948c	0.75	+0.8
3,299,427	-		Rv2948c	0.75	-0.0
3,299,489	+		Rv2948c	0.78	+0.4
3,299,498	+		Rv2948c	0.78	+0.3
3,299,498	+		Rv2948c	0.78	-0.6
3,299,498	+		Rv2948c	0.78	+0.3
3,299,498	+		Rv2948c	0.78	-0.7
3,299,498	+		Rv2948c	0.78	+0.4
3,299,499	-		Rv2948c	0.78	-0.4
3,299,499	-		Rv2948c	0.78	-1.5
3,299,499	-		Rv2948c	0.78	-0.1
3,299,500	+		Rv2948c	0.79	+0.6
3,299,500	+		Rv2948c	0.79	-0.4
3,299,500	+		Rv2948c	0.79	+0.5
3,299,500	+		Rv2948c	0.79	+1.4
3,299,500	+		Rv2948c	0.79	-0.1
3,299,500	+		Rv2948c	0.79	+0.8
3,299,501	-		Rv2948c	0.79	-1.5
3,299,501	-		Rv2948c	0.79	-0.8
3,299,501	-		Rv2948c	0.79	-0.3
3,299,501	-		Rv2948c	0.79	+0.2
3,299,501	-		Rv2948c	0.79	-0.7
3,299,504	+		Rv2948c	0.79	-0.2
3,299,504	+		Rv2948c	0.79	-0.2
3,299,504	+		Rv2948c	0.79	+0.5
3,299,505	-		Rv2948c	0.79	+0.2
3,299,505	-		Rv2948c	0.79	-0.1
3,299,505	-		Rv2948c	0.79	-0.7
3,299,509	+		Rv2948c	0.79	-1.1
3,299,509	+		Rv2948c	0.79	-0.2
3,299,509	+		Rv2948c	0.79	-0.2
3,299,509	+		Rv2948c	0.79	+0.6
3,299,510	-		Rv2948c	0.79	-0.1
3,299,510	-		Rv2948c	0.79	-0.2
3,299,539	+		Rv2948c	0.80	+0.2
3,299,539	+		Rv2948c	0.80	-0.2
3,299,742	+		Rv2948c	0.90	+0.8
3,299,742	+		Rv2948c	0.90	+0.4
3,299,878	+				+0.6
3,299,878	+				-0.6
3,299,879	-				-1.3
3,299,896	+				-0.4
3,299,896	+				-0.4
3,299,897	-				+1.0
3,299,957	-				-0.1
3,300,138	-		Rv2949c	0.28	-0.5
3,300,262	+		Rv2949c	0.48	-0.8
3,300,339	+		Rv2949c	0.61	+0.3
3,300,344	-		Rv2949c	0.62	-0.2
3,300,586	-				-0.2
3,300,688	+				-0.1
3,300,743	+				+0.4
3,300,924	+		Rv2950c	0.18	+0.8