Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2644c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
2,967,582	+		Rv2643	0.45	-0.4
2,967,583	-		Rv2643	0.45	-0.1
2,967,754	-		Rv2643	0.56	+0.4
2,967,754	-		Rv2643	0.56	+0.3
2,967,757	+		Rv2643	0.57	-0.4
2,967,861	+		Rv2643	0.64	-0.5
2,967,939	+		Rv2643	0.69	+0.3
2,967,939	+		Rv2643	0.69	-1.1
2,967,939	+		Rv2643	0.69	-1.1
2,967,940	-		Rv2643	0.69	-0.4
2,967,940	-		Rv2643	0.69	+0.9
2,968,012	+		Rv2643	0.74	-0.0
2,968,169	+		Rv2643	0.84	-0.2
2,968,260	+				-0.1
2,968,261	-				-0.3
2,968,405	-				-0.1
2,968,405	-				+0.2
2,968,405	-				-1.7
2,968,405	-				-0.2
2,968,435	-				+0.9
2,968,481	-				-1.0
2,968,534	+				+0.0
2,968,611	-		Rv2644c	0.25	+0.1
2,968,770	+		Rv2644c	0.75	+1.0
2,968,804	+		Rv2644c	0.85	-0.9
2,968,876	+				-0.1
2,968,876	+				+1.9
2,968,876	+				-0.2
2,968,877	-				-0.8
2,968,877	-				-0.9
2,969,270	+				+0.1
2,969,422	-				-0.9
2,969,428	-				-0.8
2,969,428	-				-0.1
2,969,494	+				-0.2
2,969,494	+				+0.6
2,969,495	-				+0.5
2,969,600	-				-1.6
2,969,630	+				-0.2
2,969,630	+				-0.6
2,969,631	-				-1.0
2,969,646	-				-0.9
2,969,646	-				+0.6
2,969,662	+				-0.3
2,969,662	+				-0.1
2,969,675	+				-0.3
2,969,675	+				+0.5
2,969,675	+				-1.1
2,969,835	+				-0.5
2,969,835	+				+0.3
2,969,835	+				-1.1