Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1918c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
2,166,700	-		Rv1917c	0.86	-0.4
2,166,700	-		Rv1917c	0.86	-0.4
2,166,700	-		Rv1917c	0.86	+0.9
2,166,851	+		Rv1917c	0.89	+0.1
2,166,851	+		Rv1917c	0.89	+0.5
2,166,894	-				-0.0
2,167,093	+				+0.3
2,167,094	-				-0.9
2,167,097	+				+0.2
2,167,097	+				-0.2
2,167,268	-				+0.0
2,167,413	+				-0.3
2,167,420	-				-0.3
2,167,445	+				-0.2
2,167,445	+				-0.3
2,167,650	+				+0.2
2,167,796	-				-0.0
2,167,796	-				-1.3
2,167,796	-				-0.7
2,167,806	+				+0.3
2,167,807	-				+0.5
2,167,829	+				+0.1
2,168,092	+		Rv1918c	0.15	+0.5
2,168,093	-		Rv1918c	0.15	-0.7
2,168,093	-		Rv1918c	0.15	-0.9
2,168,156	+		Rv1918c	0.17	-0.1
2,168,231	-		Rv1918c	0.20	-0.1
2,168,231	-		Rv1918c	0.20	-1.1
2,168,260	+		Rv1918c	0.21	+0.9
2,168,317	+		Rv1918c	0.23	+0.4
2,168,318	-		Rv1918c	0.23	-0.6
2,168,551	+		Rv1918c	0.30	-0.6
2,168,750	-		Rv1918c	0.37	-0.1
2,168,753	+		Rv1918c	0.37	+0.3
2,168,783	+		Rv1918c	0.38	-0.7
2,168,885	+		Rv1918c	0.42	+0.1
2,168,886	-		Rv1918c	0.42	-0.1
2,169,052	+		Rv1918c	0.47	-0.2
2,169,053	-		Rv1918c	0.47	-1.4
2,169,285	+		Rv1918c	0.55	-0.5
2,169,342	-		Rv1918c	0.57	-1.8
2,169,413	-		Rv1918c	0.60	+2.5
2,169,413	-		Rv1918c	0.60	-0.1
2,169,505	+		Rv1918c	0.63	-0.2
2,169,858	-		Rv1918c	0.75	-0.6
2,170,153	-		Rv1918c	0.84	-1.3
2,170,169	+		Rv1918c	0.85	-0.6
2,170,170	-		Rv1918c	0.85	-0.7
2,170,194	+		Rv1918c	0.86	-0.7
2,170,259	+		Rv1918c	0.88	-0.3
2,170,260	-		Rv1918c	0.88	-2.3
2,170,299	-		Rv1918c	0.89	-0.3
2,170,605	+				-0.5
2,170,605	+				-0.1
2,170,606	-				-0.5
2,171,051	+				-0.5
2,171,222	+		Rv1919c	0.35	+0.3
2,171,222	+		Rv1919c	0.35	-0.7
2,171,222	+		Rv1919c	0.35	+1.9
2,171,222	+		Rv1919c	0.35	-0.1
2,171,278	+		Rv1919c	0.47	-0.3
2,171,279	-		Rv1919c	0.47	+0.1
2,171,344	-		Rv1919c	0.61	-0.6
2,171,344	-		Rv1919c	0.61	+0.2
2,171,561	+				-0.9
2,171,576	+				-0.1
2,171,581	+				+0.4
2,171,607	+				+0.9
2,171,607	+				+0.4