Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1907c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1905c and Rv1906c are separated by 29 nucleotidesRv1906c and Rv1907c are separated by 339 nucleotidesRv1907c and Rv1908c are separated by 6 nucleotides Rv1905c: Rv1905c - Probable D-amino acid oxidase Aao, at 2,151,433 to 2,152,395 Rv1905c Rv1906c: Rv1906c - Conserved protein, at 2,152,425 to 2,152,895 Rv1906c Rv1907c: Rv1907c - Hypothetical protein, at 2,153,235 to 2,153,882 Rv1907c Rv1908c: Rv1908c - Catalase-peroxidase-peroxynitritase T KatG, at 2,153,889 to 2,156,111 Rv1908c Position (kb) 2153 2154Strain fitness (log2 ratio) -1 0 1 2 3at 2152.330 kb on + strandat 2152.330 kb on + strandat 2152.331 kb on - strandat 2152.387 kb on + strandat 2152.387 kb on + strandat 2152.388 kb on - strandat 2152.388 kb on - strandat 2152.388 kb on - strandat 2152.388 kb on - strandat 2152.491 kb on + strand, within Rv1906cat 2152.491 kb on + strand, within Rv1906cat 2152.492 kb on - strand, within Rv1906cat 2152.492 kb on - strand, within Rv1906cat 2152.612 kb on - strand, within Rv1906cat 2152.678 kb on + strand, within Rv1906cat 2152.748 kb on - strand, within Rv1906cat 2152.748 kb on - strand, within Rv1906cat 2152.903 kb on + strandat 2152.903 kb on + strandat 2152.903 kb on + strandat 2152.904 kb on - strandat 2152.909 kb on - strandat 2152.994 kb on + strandat 2152.994 kb on + strandat 2153.125 kb on + strandat 2153.386 kb on + strand, within Rv1907cat 2153.387 kb on - strand, within Rv1907cat 2153.408 kb on + strand, within Rv1907cat 2153.409 kb on - strand, within Rv1907cat 2153.619 kb on + strand, within Rv1907cat 2153.665 kb on + strand, within Rv1907cat 2153.665 kb on + strand, within Rv1907cat 2153.666 kb on - strand, within Rv1907cat 2153.981 kb on - strandat 2154.289 kb on + strand, within Rv1908cat 2154.835 kb on + strand, within Rv1908c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Clarithromycin 0.967 ug/mL
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2,152,330 + -1.7
2,152,330 + +0.2
2,152,331 - +0.9
2,152,387 + +0.9
2,152,387 + -0.7
2,152,388 - +0.1
2,152,388 - +0.4
2,152,388 - +0.5
2,152,388 - +3.2
2,152,491 + Rv1906c 0.14 -0.0
2,152,491 + Rv1906c 0.14 +0.1
2,152,492 - Rv1906c 0.14 +0.2
2,152,492 - Rv1906c 0.14 +0.1
2,152,612 - Rv1906c 0.40 +0.3
2,152,678 + Rv1906c 0.54 -0.1
2,152,748 - Rv1906c 0.69 +0.9
2,152,748 - Rv1906c 0.69 -0.4
2,152,903 + +0.2
2,152,903 + +0.1
2,152,903 + +0.3
2,152,904 - -0.6
2,152,909 - -0.2
2,152,994 + -0.1
2,152,994 + +0.2
2,153,125 + -0.3
2,153,386 + Rv1907c 0.23 -0.1
2,153,387 - Rv1907c 0.23 -1.7
2,153,408 + Rv1907c 0.27 +0.0
2,153,409 - Rv1907c 0.27 -1.1
2,153,619 + Rv1907c 0.59 -1.3
2,153,665 + Rv1907c 0.66 -0.7
2,153,665 + Rv1907c 0.66 -1.6
2,153,666 - Rv1907c 0.67 +0.0
2,153,981 - -0.1
2,154,289 + Rv1908c 0.18 -1.0
2,154,835 + Rv1908c 0.43 -0.1

Or see this region's nucleotide sequence