Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1584c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1582c and Rv1583c overlap by 1 nucleotidesRv1583c and Rv1584c overlap by 4 nucleotidesRv1584c and Rv1585c are separated by 55 nucleotidesRv1585c and Rv1586c overlap by 4 nucleotides Rv1582c: Rv1582c - Probable PhiRv1 phage protein, at 1,784,497 to 1,785,912 Rv1582c Rv1583c: Rv1583c - Probable PhiRv1 phage protein, at 1,785,912 to 1,786,310 Rv1583c Rv1584c: Rv1584c - Possible PhiRv1 phage protein, at 1,786,307 to 1,786,528 Rv1584c Rv1585c: Rv1585c - Possible phage PhiRv1 protein, at 1,786,584 to 1,787,099 Rv1585c Rv1586c: Rv1586c - Probable PhiRv1 integrase, at 1,787,096 to 1,788,505 Rv1586c Position (kb) 1786 1787Strain fitness (log2 ratio) -1 0 1at 1785.308 kb on - strand, within Rv1582cat 1785.424 kb on + strand, within Rv1582cat 1785.551 kb on - strand, within Rv1582cat 1786.410 kb on + strand, within Rv1584cat 1786.410 kb on + strand, within Rv1584cat 1786.411 kb on - strand, within Rv1584cat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.592 kb on + strandat 1786.614 kb on + strandat 1786.706 kb on - strand, within Rv1585cat 1786.974 kb on + strand, within Rv1585c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Clarithromycin 0.967 ug/mL
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1,785,308 - Rv1582c 0.57 +0.4
1,785,424 + Rv1582c 0.65 -0.6
1,785,551 - Rv1582c 0.74 -0.5
1,786,410 + Rv1584c 0.46 +1.3
1,786,410 + Rv1584c 0.46 -0.1
1,786,411 - Rv1584c 0.47 +0.1
1,786,515 + -0.1
1,786,515 + +0.1
1,786,515 + +0.1
1,786,515 + +0.0
1,786,515 + -1.4
1,786,592 + -0.4
1,786,614 + -0.7
1,786,706 - Rv1585c 0.24 -0.2
1,786,974 + Rv1585c 0.76 +0.3

Or see this region's nucleotide sequence