Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1286

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
1,437,907	-				-0.1
1,438,624	-		Rv1285	0.72	-0.8
1,439,133	-		Rv1286	0.12	+1.2
1,439,189	+		Rv1286	0.15	-1.4
1,439,792	-		Rv1286	0.48	+0.1
1,439,906	+		Rv1286	0.54	+2.1
1,439,906	+		Rv1286	0.54	+1.8
1,440,151	-		Rv1286	0.67	-0.2
1,440,329	+		Rv1286	0.77	-0.0
1,440,352	-		Rv1286	0.78	+0.9
1,440,508	+		Rv1286	0.87	+0.4
1,440,599	+				+0.2
1,440,599	+				+0.1
1,440,600	-				+0.0
1,440,600	-				+0.1
1,440,653	+				+0.9
1,440,679	-				+0.4
1,440,703	-				-0.1
1,440,749	+				-1.1
1,440,914	+		Rv1287	0.22	+1.9
1,440,914	+		Rv1287	0.22	+0.6
1,440,915	-		Rv1287	0.23	-0.6
1,441,041	-		Rv1287	0.49	-0.9
1,441,156	-		Rv1287	0.72	-1.1
1,441,336	-				-0.2
1,441,408	+				+0.3
1,441,426	+				+0.1
1,441,494	+		Rv1288	0.11	-0.7
1,441,494	+		Rv1288	0.11	+1.5
1,441,495	-		Rv1288	0.11	-0.6
1,441,513	+		Rv1288	0.12	+1.4
1,441,514	-		Rv1288	0.12	+0.6
1,441,514	-		Rv1288	0.12	+0.0
1,441,514	-		Rv1288	0.12	+0.6
1,441,561	+		Rv1288	0.16	-0.2
1,441,666	+		Rv1288	0.23	+0.8
1,441,666	+		Rv1288	0.23	-0.0
1,441,730	+		Rv1288	0.28	-0.0
1,441,730	+		Rv1288	0.28	-0.6
1,441,731	-		Rv1288	0.28	-0.2
1,441,731	-		Rv1288	0.28	-0.2
1,441,731	-		Rv1288	0.28	+0.5