Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1231c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
1,373,398	-		Rv1230c	0.35	+0.3
1,373,410	+		Rv1230c	0.36	+0.1
1,373,566	+		Rv1230c	0.49	+0.6
1,373,567	-		Rv1230c	0.49	-0.6
1,373,617	+		Rv1230c	0.53	+0.4
1,373,692	+		Rv1230c	0.59	-1.2
1,373,915	+		Rv1230c	0.77	-0.0
1,373,916	-		Rv1230c	0.77	-0.1
1,373,916	-		Rv1230c	0.77	-0.4
1,373,983	-		Rv1230c	0.83	+0.3
1,374,232	+				-0.2
1,374,233	-				+0.9
1,374,233	-				-0.1
1,374,233	-				+1.6
1,374,243	-				+0.2
1,374,267	+				-0.1
1,374,267	+				-0.2
1,374,278	-				-0.1
1,374,444	-		Rv1231c	0.22	+0.1
1,374,503	+		Rv1231c	0.33	+0.6
1,374,503	+		Rv1231c	0.33	-0.1
1,374,503	+		Rv1231c	0.33	+0.1
1,374,504	-		Rv1231c	0.34	+0.3
1,374,611	+		Rv1231c	0.53	+2.6
1,374,709	+		Rv1231c	0.71	+0.6
1,374,709	+		Rv1231c	0.71	+1.3
1,374,734	+		Rv1231c	0.76	+0.3
1,374,833	+				+1.0
1,374,833	+				+0.3
1,374,914	+				+1.2
1,374,914	+				+0.9
1,374,939	+				+0.2
1,374,939	+				-0.0
1,374,939	+				+0.3
1,374,939	+				+1.3
1,374,939	+				+1.0
1,374,939	+				+0.9
1,374,940	-				-1.1
1,375,033	+		Rv1232c	0.13	+0.1
1,375,764	-		Rv1232c	0.69	+0.1