Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1028c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clarithromycin 0.967 ug/mL
1,148,113	+				+0.9
1,148,113	+				+0.4
1,148,114	-				+0.6
1,148,114	-				-0.2
1,148,388	-				+0.9
1,148,753	+		Rv1027c	0.48	+0.5
1,148,754	-		Rv1027c	0.48	-0.3
1,149,053	+				+0.2
1,149,054	-				-0.1
1,149,164	-				-0.2
1,149,328	+				-0.3
1,149,387	+		Rv1028c	0.11	+0.1
1,150,074	+		Rv1028c	0.38	+0.3
1,150,074	+		Rv1028c	0.38	-0.2
1,150,287	+		Rv1028c	0.46	+0.4
1,150,309	-		Rv1028c	0.47	+0.0
1,151,049	+		Rv1028c	0.75	+0.6
1,151,226	-		Rv1028c	0.82	-0.3
1,151,592	+				+1.5
1,151,731	-				+0.9
1,152,087	+				-0.7
1,152,163	-				-0.4
1,152,170	-				-0.8
1,152,210	+		Rv1029	0.12	-0.6
1,152,210	+		Rv1029	0.12	-0.4
1,152,211	-		Rv1029	0.12	+0.4
1,152,239	+		Rv1029	0.13	+0.3
1,152,239	+		Rv1029	0.13	+1.5
1,152,239	+		Rv1029	0.13	-0.4
1,152,239	+		Rv1029	0.13	+0.2
1,152,240	-		Rv1029	0.13	+2.9
1,152,258	+		Rv1029	0.14	+0.3
1,152,259	-		Rv1029	0.14	+0.4
1,152,379	-		Rv1029	0.21	-0.0