Experiment: 7H9 with Clarithromycin 0.967 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1001 and Rv1002c are separated by 34 nucleotides Rv1002c and Rv1003 are separated by 82 nucleotides Rv1003 and Rv1004c are separated by 9 nucleotides
Rv1001: Rv1001 - Probable arginine deiminase ArcA (adi) (ad) (arginine dihydrolase), at 1,117,185 to 1,118,393
Rv1001
Rv1002c: Rv1002c - Conserved membrane protein, at 1,118,428 to 1,119,939
Rv1002c
Rv1003: Rv1003 - Conserved protein, at 1,120,022 to 1,120,879
Rv1003
Rv1004c: Rv1004c - Probable membrane protein, at 1,120,889 to 1,122,148
Rv1004c
Position (kb)
1118
1119
1120 Strain fitness (log2 ratio)
-2
-1
0
1 at 1117.515 kb on - strand, within Rv1001 at 1117.613 kb on + strand, within Rv1001 at 1117.721 kb on - strand, within Rv1001 at 1117.761 kb on + strand, within Rv1001 at 1117.761 kb on + strand, within Rv1001 at 1117.762 kb on - strand, within Rv1001 at 1117.762 kb on - strand, within Rv1001 at 1117.762 kb on - strand, within Rv1001 at 1117.762 kb on - strand, within Rv1001 at 1117.762 kb on - strand, within Rv1001 at 1117.800 kb on + strand, within Rv1001 at 1118.021 kb on + strand, within Rv1001 at 1118.022 kb on - strand, within Rv1001 at 1118.269 kb on + strand, within Rv1001 at 1118.270 kb on - strand, within Rv1001 at 1118.270 kb on - strand, within Rv1001 at 1118.392 kb on - strand at 1120.009 kb on + strand at 1120.010 kb on - strand at 1120.360 kb on - strand, within Rv1003 at 1120.878 kb on - strand at 1120.878 kb on - strand at 1120.890 kb on + strand at 1120.897 kb on + strand at 1120.897 kb on + strand at 1120.897 kb on + strand at 1120.898 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clarithromycin 0.967 ug/mL remove 1,117,515 - Rv1001 0.27 -0.7 1,117,613 + Rv1001 0.35 +0.1 1,117,721 - Rv1001 0.44 +0.4 1,117,761 + Rv1001 0.48 +0.9 1,117,761 + Rv1001 0.48 -0.0 1,117,762 - Rv1001 0.48 -0.3 1,117,762 - Rv1001 0.48 +0.9 1,117,762 - Rv1001 0.48 -0.2 1,117,762 - Rv1001 0.48 +0.2 1,117,762 - Rv1001 0.48 -0.2 1,117,800 + Rv1001 0.51 +0.4 1,118,021 + Rv1001 0.69 -0.8 1,118,022 - Rv1001 0.69 -0.0 1,118,269 + Rv1001 0.90 -0.2 1,118,270 - Rv1001 0.90 -0.4 1,118,270 - Rv1001 0.90 -0.2 1,118,392 - -0.6 1,120,009 + +0.9 1,120,010 - -0.3 1,120,360 - Rv1003 0.39 -0.9 1,120,878 - +0.4 1,120,878 - -1.9 1,120,890 + -0.2 1,120,897 + +0.1 1,120,897 + -1.4 1,120,897 + +0.5 1,120,898 - +0.7
Or see this region's nucleotide sequence