Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0964c

Experiment: 7H9 with Clarithromycin 0.967 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0963c and Rv0964c are separated by 98 nucleotidesRv0964c and Rv0965c are separated by 99 nucleotidesRv0965c and Rv0966c are separated by 35 nucleotides Rv0963c: Rv0963c - Conserved hypothetical protein, at 1,075,297 to 1,076,097 Rv0963c Rv0964c: Rv0964c - Hypothetical protein, at 1,076,196 to 1,076,678 Rv0964c Rv0965c: Rv0965c - Conserved hypothetical protein, at 1,076,778 to 1,077,197 Rv0965c Rv0966c: Rv0966c - Conserved protein, at 1,077,233 to 1,077,835 Rv0966c Position (kb) 1076 1077Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1075.241 kb on + strandat 1075.275 kb on + strandat 1075.298 kb on + strandat 1075.298 kb on + strandat 1075.425 kb on + strand, within Rv0963cat 1075.425 kb on + strand, within Rv0963cat 1075.425 kb on + strand, within Rv0963cat 1075.457 kb on + strand, within Rv0963cat 1075.458 kb on - strand, within Rv0963cat 1075.523 kb on + strand, within Rv0963cat 1075.524 kb on - strand, within Rv0963cat 1075.728 kb on - strand, within Rv0963cat 1075.760 kb on + strand, within Rv0963cat 1075.761 kb on - strand, within Rv0963cat 1075.993 kb on - strand, within Rv0963cat 1076.474 kb on - strand, within Rv0964cat 1076.520 kb on + strand, within Rv0964cat 1076.521 kb on - strand, within Rv0964cat 1076.631 kb on + strandat 1076.632 kb on - strandat 1076.784 kb on - strandat 1076.784 kb on - strandat 1076.899 kb on + strand, within Rv0965cat 1076.899 kb on + strand, within Rv0965cat 1077.121 kb on + strand, within Rv0965cat 1077.121 kb on + strand, within Rv0965cat 1077.122 kb on - strand, within Rv0965cat 1077.122 kb on - strand, within Rv0965cat 1077.617 kb on + strand, within Rv0966cat 1077.618 kb on - strand, within Rv0966cat 1077.663 kb on + strand, within Rv0966cat 1077.678 kb on + strand, within Rv0966c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Clarithromycin 0.967 ug/mL
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1,075,241 + -0.2
1,075,275 + -0.2
1,075,298 + -1.7
1,075,298 + +0.2
1,075,425 + Rv0963c 0.16 +0.2
1,075,425 + Rv0963c 0.16 -1.9
1,075,425 + Rv0963c 0.16 +0.8
1,075,457 + Rv0963c 0.20 -0.4
1,075,458 - Rv0963c 0.20 -1.2
1,075,523 + Rv0963c 0.28 -0.2
1,075,524 - Rv0963c 0.28 +0.3
1,075,728 - Rv0963c 0.54 -0.3
1,075,760 + Rv0963c 0.58 -1.0
1,075,761 - Rv0963c 0.58 +0.4
1,075,993 - Rv0963c 0.87 -0.8
1,076,474 - Rv0964c 0.58 +3.5
1,076,520 + Rv0964c 0.67 -0.3
1,076,521 - Rv0964c 0.67 +1.7
1,076,631 + -0.3
1,076,632 - -0.3
1,076,784 - +0.0
1,076,784 - -1.3
1,076,899 + Rv0965c 0.29 +0.5
1,076,899 + Rv0965c 0.29 -0.3
1,077,121 + Rv0965c 0.82 +0.7
1,077,121 + Rv0965c 0.82 -0.3
1,077,122 - Rv0965c 0.82 -0.4
1,077,122 - Rv0965c 0.82 -0.3
1,077,617 + Rv0966c 0.64 +0.2
1,077,618 - Rv0966c 0.64 -1.4
1,077,663 + Rv0966c 0.71 -1.7
1,077,678 + Rv0966c 0.74 +0.1

Or see this region's nucleotide sequence