Experiment: 7H9 with Clarithromycin 0.967 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0555 and Rv0556 overlap by 4 nucleotides Rv0556 and Rv0557 are separated by 61 nucleotides Rv0557 and Rv0558 are separated by 16 nucleotides Rv0558 and Rv0559c are separated by 13 nucleotides
Rv0555: Rv0555 - Probable bifunctional menaquinone biosynthesis protein MenD : 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (SHCHC synthase) + 2-oxoglutarate decarboxylase (alpha-ketoglutarate decarboxylase) (KDC), at 646,298 to 647,962
Rv0555
Rv0556: Rv0556 - Probable conserved transmembrane protein, at 647,959 to 648,474
Rv0556
Rv0557: Rv0557 - Mannosyltransferase MgtA, at 648,536 to 649,672
Rv0557
Rv0558: Rv0558 - Probable ubiquinone/menaquinone biosynthesis methyltransferase MenH (2-heptaprenyl-1,4-naphthoquinone methyltransferase), at 649,689 to 650,393
Rv0558
Rv0559c: Rv0559c - Possible conserved secreted protein, at 650,407 to 650,745
Rv0559c
Position (kb) 648
649
650 Strain fitness (log2 ratio) -1
0
1 at 648.417 kb on - strand, within Rv0556 at 648.496 kb on - strand at 648.496 kb on - strand at 649.464 kb on + strand, within Rv0557 at 649.632 kb on - strand at 649.688 kb on + strand at 650.454 kb on - strand, within Rv0559c at 650.543 kb on + strand, within Rv0559c at 650.543 kb on + strand, within Rv0559c at 650.543 kb on + strand, within Rv0559c at 650.544 kb on - strand, within Rv0559c at 650.607 kb on - strand, within Rv0559c at 650.621 kb on + strand, within Rv0559c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clarithromycin 0.967 ug/mL remove 648,417 - Rv0556 0.89 -0.7 648,496 - +0.5 648,496 - -0.4 649,464 + Rv0557 0.82 +0.2 649,632 - -0.2 649,688 + -0.5 650,454 - Rv0559c 0.14 -0.1 650,543 + Rv0559c 0.40 -0.3 650,543 + Rv0559c 0.40 -0.1 650,543 + Rv0559c 0.40 -0.0 650,544 - Rv0559c 0.40 -0.1 650,607 - Rv0559c 0.59 -0.6 650,621 + Rv0559c 0.63 -0.0
Or see this region's nucleotide sequence