Experiment: 7H9 with Clarithromycin 0.967 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0302 and Rv0303 overlap by 4 nucleotides Rv0303 and Rv0304c are separated by 7 nucleotides Rv0304c and Rv0305c are separated by 55 nucleotides
Rv0302: Rv0302 - Probable transcriptional regulatory protein (probably TetR/AcrR-family), at 364,605 to 365,237
Rv0302
Rv0303: Rv0303 - Probable dehydrogenase/reductase, at 365,234 to 366,142
Rv0303
Rv0304c: Rv0304c - PPE family protein PPE5, at 366,150 to 372,764
Rv0304c
Rv0305c: Rv0305c - PPE family protein PPE6, at 372,820 to 375,711
Rv0305c
Position (kb) 366
367
368
369
370
371
372
373 Strain fitness (log2 ratio) -2
-1
0
1
2 at 365.178 kb on + strand at 365.179 kb on - strand at 365.179 kb on - strand at 365.304 kb on + strand at 365.565 kb on + strand, within Rv0303 at 365.693 kb on + strand, within Rv0303 at 365.695 kb on + strand, within Rv0303 at 365.696 kb on - strand, within Rv0303 at 365.696 kb on - strand, within Rv0303 at 365.696 kb on - strand, within Rv0303 at 365.762 kb on + strand, within Rv0303 at 365.762 kb on + strand, within Rv0303 at 365.798 kb on + strand, within Rv0303 at 365.799 kb on - strand, within Rv0303 at 365.865 kb on + strand, within Rv0303 at 365.918 kb on + strand, within Rv0303 at 365.918 kb on + strand, within Rv0303 at 366.077 kb on + strand at 366.140 kb on + strand at 366.140 kb on + strand at 366.140 kb on + strand at 366.141 kb on - strand at 366.141 kb on - strand at 366.141 kb on - strand at 366.141 kb on - strand at 366.159 kb on - strand at 366.189 kb on - strand at 366.452 kb on - strand at 366.482 kb on - strand at 366.735 kb on - strand at 366.735 kb on - strand at 366.887 kb on + strand, within Rv0304c at 366.908 kb on - strand, within Rv0304c at 366.908 kb on - strand, within Rv0304c at 366.968 kb on - strand, within Rv0304c at 366.968 kb on - strand, within Rv0304c at 367.027 kb on + strand, within Rv0304c at 367.027 kb on + strand, within Rv0304c at 367.161 kb on - strand, within Rv0304c at 367.346 kb on - strand, within Rv0304c at 367.512 kb on + strand, within Rv0304c at 367.512 kb on + strand, within Rv0304c at 367.512 kb on + strand, within Rv0304c at 367.513 kb on - strand, within Rv0304c at 367.513 kb on - strand, within Rv0304c at 367.513 kb on - strand, within Rv0304c at 367.513 kb on - strand, within Rv0304c at 367.513 kb on - strand, within Rv0304c at 367.513 kb on - strand, within Rv0304c at 367.809 kb on + strand, within Rv0304c at 367.809 kb on + strand, within Rv0304c at 367.809 kb on + strand, within Rv0304c at 367.810 kb on - strand, within Rv0304c at 367.835 kb on - strand, within Rv0304c at 367.922 kb on - strand, within Rv0304c at 367.981 kb on + strand, within Rv0304c at 367.982 kb on - strand, within Rv0304c at 367.982 kb on - strand, within Rv0304c at 368.012 kb on - strand, within Rv0304c at 368.066 kb on + strand, within Rv0304c at 368.290 kb on - strand, within Rv0304c at 368.417 kb on + strand, within Rv0304c at 368.452 kb on + strand, within Rv0304c at 368.452 kb on + strand, within Rv0304c at 368.452 kb on + strand, within Rv0304c at 368.453 kb on - strand, within Rv0304c at 368.453 kb on - strand, within Rv0304c at 368.453 kb on - strand, within Rv0304c at 368.453 kb on - strand, within Rv0304c at 368.453 kb on - strand, within Rv0304c at 368.482 kb on + strand, within Rv0304c at 368.482 kb on + strand, within Rv0304c at 368.723 kb on - strand, within Rv0304c at 368.723 kb on - strand, within Rv0304c at 368.723 kb on - strand, within Rv0304c at 368.723 kb on - strand, within Rv0304c at 368.723 kb on - strand, within Rv0304c at 369.098 kb on + strand, within Rv0304c at 369.177 kb on + strand, within Rv0304c at 369.177 kb on + strand, within Rv0304c at 369.178 kb on - strand, within Rv0304c at 369.224 kb on + strand, within Rv0304c at 369.225 kb on - strand, within Rv0304c at 369.241 kb on + strand, within Rv0304c at 369.444 kb on - strand, within Rv0304c at 369.444 kb on - strand, within Rv0304c at 369.573 kb on - strand, within Rv0304c at 369.745 kb on + strand, within Rv0304c at 369.745 kb on + strand, within Rv0304c at 369.746 kb on - strand, within Rv0304c at 369.746 kb on - strand, within Rv0304c at 369.753 kb on + strand, within Rv0304c at 369.805 kb on + strand, within Rv0304c at 369.805 kb on + strand, within Rv0304c at 369.805 kb on + strand, within Rv0304c at 369.973 kb on + strand, within Rv0304c at 369.974 kb on - strand, within Rv0304c at 370.002 kb on - strand, within Rv0304c at 370.002 kb on - strand, within Rv0304c at 370.002 kb on - strand, within Rv0304c at 370.037 kb on - strand, within Rv0304c at 370.208 kb on + strand, within Rv0304c at 370.262 kb on + strand, within Rv0304c at 370.263 kb on - strand, within Rv0304c at 370.263 kb on - strand, within Rv0304c at 370.263 kb on - strand, within Rv0304c at 370.301 kb on + strand, within Rv0304c at 370.314 kb on + strand, within Rv0304c at 370.314 kb on + strand, within Rv0304c at 370.315 kb on - strand, within Rv0304c at 370.367 kb on + strand, within Rv0304c at 370.368 kb on - strand, within Rv0304c at 370.447 kb on + strand, within Rv0304c at 371.026 kb on - strand, within Rv0304c at 371.114 kb on - strand, within Rv0304c at 371.281 kb on + strand, within Rv0304c at 371.281 kb on + strand, within Rv0304c at 371.281 kb on + strand, within Rv0304c at 371.282 kb on - strand, within Rv0304c at 371.516 kb on + strand, within Rv0304c at 371.610 kb on - strand, within Rv0304c at 371.687 kb on + strand, within Rv0304c at 371.800 kb on + strand, within Rv0304c at 371.811 kb on + strand, within Rv0304c at 371.812 kb on - strand, within Rv0304c at 371.812 kb on - strand, within Rv0304c at 371.890 kb on + strand, within Rv0304c at 371.890 kb on + strand, within Rv0304c at 371.891 kb on - strand, within Rv0304c at 371.969 kb on + strand, within Rv0304c at 372.346 kb on + strand at 372.347 kb on - strand at 372.406 kb on + strand at 372.495 kb on - strand at 372.554 kb on + strand at 372.555 kb on - strand at 372.557 kb on + strand at 372.596 kb on + strand at 372.609 kb on - strand at 372.665 kb on - strand at 372.765 kb on - strand at 372.765 kb on - strand at 372.881 kb on + strand at 372.882 kb on - strand at 372.988 kb on - strand at 373.076 kb on - strand at 373.077 kb on + strand at 373.078 kb on - strand at 373.078 kb on - strand at 373.108 kb on - strand at 373.108 kb on - strand at 373.314 kb on - strand, within Rv0305c at 373.314 kb on - strand, within Rv0305c at 373.314 kb on - strand, within Rv0305c at 373.317 kb on + strand, within Rv0305c at 373.373 kb on + strand, within Rv0305c at 373.373 kb on + strand, within Rv0305c at 373.373 kb on + strand, within Rv0305c at 373.373 kb on + strand, within Rv0305c at 373.373 kb on + strand, within Rv0305c at 373.373 kb on + strand, within Rv0305c at 373.393 kb on - strand, within Rv0305c at 373.675 kb on - strand, within Rv0305c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clarithromycin 0.967 ug/mL remove 365,178 + -0.2 365,179 - -0.3 365,179 - -0.0 365,304 + +0.1 365,565 + Rv0303 0.36 +0.5 365,693 + Rv0303 0.50 -0.8 365,695 + Rv0303 0.51 -0.5 365,696 - Rv0303 0.51 -0.3 365,696 - Rv0303 0.51 -0.5 365,696 - Rv0303 0.51 -0.6 365,762 + Rv0303 0.58 -0.1 365,762 + Rv0303 0.58 -0.3 365,798 + Rv0303 0.62 -0.4 365,799 - Rv0303 0.62 -1.0 365,865 + Rv0303 0.69 +0.2 365,918 + Rv0303 0.75 -0.3 365,918 + Rv0303 0.75 -0.6 366,077 + -0.1 366,140 + -0.0 366,140 + -0.1 366,140 + -0.5 366,141 - +0.4 366,141 - -0.5 366,141 - -0.3 366,141 - +1.1 366,159 - +0.3 366,189 - +0.2 366,452 - +0.2 366,482 - -0.5 366,735 - -0.8 366,735 - -0.7 366,887 + Rv0304c 0.11 -0.2 366,908 - Rv0304c 0.11 +1.0 366,908 - Rv0304c 0.11 +0.4 366,968 - Rv0304c 0.12 -0.1 366,968 - Rv0304c 0.12 -0.7 367,027 + Rv0304c 0.13 +0.9 367,027 + Rv0304c 0.13 +0.2 367,161 - Rv0304c 0.15 -0.2 367,346 - Rv0304c 0.18 +0.1 367,512 + Rv0304c 0.21 -1.9 367,512 + Rv0304c 0.21 -0.0 367,512 + Rv0304c 0.21 -0.1 367,513 - Rv0304c 0.21 -0.1 367,513 - Rv0304c 0.21 -0.2 367,513 - Rv0304c 0.21 -0.9 367,513 - Rv0304c 0.21 +0.4 367,513 - Rv0304c 0.21 +0.6 367,513 - Rv0304c 0.21 -1.6 367,809 + Rv0304c 0.25 +0.1 367,809 + Rv0304c 0.25 -0.4 367,809 + Rv0304c 0.25 -0.0 367,810 - Rv0304c 0.25 +0.1 367,835 - Rv0304c 0.25 -0.7 367,922 - Rv0304c 0.27 -0.1 367,981 + Rv0304c 0.28 -1.7 367,982 - Rv0304c 0.28 -0.6 367,982 - Rv0304c 0.28 -1.1 368,012 - Rv0304c 0.28 +0.3 368,066 + Rv0304c 0.29 -0.1 368,290 - Rv0304c 0.32 +0.3 368,417 + Rv0304c 0.34 -0.8 368,452 + Rv0304c 0.35 -0.3 368,452 + Rv0304c 0.35 +0.1 368,452 + Rv0304c 0.35 -0.0 368,453 - Rv0304c 0.35 -0.6 368,453 - Rv0304c 0.35 +1.2 368,453 - Rv0304c 0.35 -0.4 368,453 - Rv0304c 0.35 -0.2 368,453 - Rv0304c 0.35 -0.1 368,482 + Rv0304c 0.35 -0.3 368,482 + Rv0304c 0.35 -0.1 368,723 - Rv0304c 0.39 -0.1 368,723 - Rv0304c 0.39 -1.1 368,723 - Rv0304c 0.39 -0.5 368,723 - Rv0304c 0.39 +0.3 368,723 - Rv0304c 0.39 -0.1 369,098 + Rv0304c 0.45 -0.8 369,177 + Rv0304c 0.46 +0.2 369,177 + Rv0304c 0.46 +0.1 369,178 - Rv0304c 0.46 -0.1 369,224 + Rv0304c 0.46 -0.1 369,225 - Rv0304c 0.46 -0.3 369,241 + Rv0304c 0.47 -0.1 369,444 - Rv0304c 0.50 +0.9 369,444 - Rv0304c 0.50 +0.9 369,573 - Rv0304c 0.52 -0.0 369,745 + Rv0304c 0.54 -0.5 369,745 + Rv0304c 0.54 +0.5 369,746 - Rv0304c 0.54 +0.2 369,746 - Rv0304c 0.54 +0.9 369,753 + Rv0304c 0.54 -0.3 369,805 + Rv0304c 0.55 -0.5 369,805 + Rv0304c 0.55 +0.1 369,805 + Rv0304c 0.55 -0.3 369,973 + Rv0304c 0.58 -0.1 369,974 - Rv0304c 0.58 +0.9 370,002 - Rv0304c 0.58 -0.9 370,002 - Rv0304c 0.58 +0.9 370,002 - Rv0304c 0.58 +0.1 370,037 - Rv0304c 0.59 -0.6 370,208 + Rv0304c 0.61 -1.0 370,262 + Rv0304c 0.62 +0.5 370,263 - Rv0304c 0.62 +0.1 370,263 - Rv0304c 0.62 +0.0 370,263 - Rv0304c 0.62 +0.7 370,301 + Rv0304c 0.63 -0.5 370,314 + Rv0304c 0.63 +0.5 370,314 + Rv0304c 0.63 -0.8 370,315 - Rv0304c 0.63 +0.9 370,367 + Rv0304c 0.64 +0.4 370,368 - Rv0304c 0.64 -0.0 370,447 + Rv0304c 0.65 -0.3 371,026 - Rv0304c 0.74 -0.7 371,114 - Rv0304c 0.75 +0.4 371,281 + Rv0304c 0.78 -0.8 371,281 + Rv0304c 0.78 -0.4 371,281 + Rv0304c 0.78 +0.2 371,282 - Rv0304c 0.78 -1.0 371,516 + Rv0304c 0.81 -0.1 371,610 - Rv0304c 0.83 +0.1 371,687 + Rv0304c 0.84 -0.1 371,800 + Rv0304c 0.85 -0.4 371,811 + Rv0304c 0.86 +0.9 371,812 - Rv0304c 0.86 -1.1 371,812 - Rv0304c 0.86 +0.0 371,890 + Rv0304c 0.87 +0.3 371,890 + Rv0304c 0.87 -2.6 371,891 - Rv0304c 0.87 -0.2 371,969 + Rv0304c 0.88 -0.9 372,346 + +0.6 372,347 - -0.7 372,406 + +1.9 372,495 - -0.9 372,554 + -0.1 372,555 - +0.1 372,557 + -1.3 372,596 + -1.0 372,609 - -0.2 372,665 - -0.8 372,765 - -0.2 372,765 - -0.7 372,881 + -0.5 372,882 - +0.6 372,988 - -0.1 373,076 - -0.3 373,077 + +0.8 373,078 - -0.1 373,078 - -0.3 373,108 - +0.8 373,108 - -0.1 373,314 - Rv0305c 0.17 +0.0 373,314 - Rv0305c 0.17 +0.6 373,314 - Rv0305c 0.17 -0.6 373,317 + Rv0305c 0.17 +0.1 373,373 + Rv0305c 0.19 +0.6 373,373 + Rv0305c 0.19 -0.2 373,373 + Rv0305c 0.19 -0.6 373,373 + Rv0305c 0.19 +1.6 373,373 + Rv0305c 0.19 +0.3 373,373 + Rv0305c 0.19 +0.3 373,393 - Rv0305c 0.20 -0.6 373,675 - Rv0305c 0.30 -0.7
Or see this region's nucleotide sequence