Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3559c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
3,998,735	+		Rv3558	0.46	+0.2
3,998,991	-		Rv3558	0.61	+0.2
3,999,078	-		Rv3558	0.66	-0.4
3,999,220	+		Rv3558	0.75	+0.2
3,999,220	+		Rv3558	0.75	-0.3
3,999,445	+		Rv3558	0.88	-2.2
3,999,585	-				-0.4
4,000,012	-		Rv3559c	0.46	+0.4
4,000,012	-		Rv3559c	0.46	+1.7
4,000,535	+				-0.3
4,000,535	+				+0.0
4,000,536	-				+0.0
4,000,536	-				-0.3
4,000,536	-				-0.3
4,000,707	-		Rv3560c	0.24	-0.7
4,001,031	-		Rv3560c	0.52	+1.3
4,001,132	-		Rv3560c	0.60	+1.1
4,001,208	-		Rv3560c	0.67	-0.6
4,001,352	-		Rv3560c	0.79	-1.0
4,001,352	-		Rv3560c	0.79	-0.2
4,001,352	-		Rv3560c	0.79	-0.6