Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3431c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
3,848,324	+		Rv3430c	0.59	-0.2
3,848,325	-		Rv3430c	0.59	-0.2
3,848,325	-		Rv3430c	0.59	-0.4
3,848,330	+		Rv3430c	0.59	-0.1
3,848,336	+		Rv3430c	0.60	-1.4
3,848,371	-		Rv3430c	0.63	-0.2
3,848,487	-		Rv3430c	0.73	+0.0
3,848,510	+		Rv3430c	0.75	+0.6
3,848,510	+		Rv3430c	0.75	-0.5
3,848,511	-		Rv3430c	0.75	+0.6
3,848,511	-		Rv3430c	0.75	+0.9
3,848,537	+		Rv3430c	0.77	-0.0
3,848,537	+		Rv3430c	0.77	-0.0
3,848,537	+		Rv3430c	0.77	-0.1
3,848,538	-		Rv3430c	0.77	+0.1
3,848,538	-		Rv3430c	0.77	-1.3
3,848,590	+		Rv3430c	0.81	+0.2
3,848,591	-		Rv3430c	0.82	+0.1
3,848,680	-		Rv3430c	0.89	+0.4
3,848,720	+				+0.6
3,849,100	+				+1.7
3,849,100	+				+0.3
3,849,101	-				+1.1
3,849,101	-				-1.5
3,849,124	+				-0.3
3,849,124	+				+1.0
3,849,141	-				-0.1
3,849,216	-				+0.5
3,849,224	+				-0.2
3,849,225	-				+1.1
3,849,227	+				-0.7
3,849,721	+		Rv3431c	0.50	-0.2
3,849,722	-		Rv3431c	0.51	+0.5
3,849,722	-		Rv3431c	0.51	+0.6
3,849,809	+		Rv3431c	0.61	+0.2
3,849,880	+		Rv3431c	0.69	-0.2
3,849,880	+		Rv3431c	0.69	-0.1
3,849,881	-		Rv3431c	0.69	+0.8
3,850,275	-				+0.2
3,850,330	+				-0.1
3,850,330	+				-1.5
3,850,330	+				+0.1
3,850,330	+				-0.4
3,850,370	+				+0.7
3,850,371	-				-0.3
3,850,373	+				-0.8
3,850,373	+				-0.5
3,850,374	-				-0.1
3,850,374	-				-0.7
3,850,734	+		Rv3432c	0.26	-0.7
3,850,734	+		Rv3432c	0.26	-0.9
3,850,735	-		Rv3432c	0.26	-0.8
3,850,735	-		Rv3432c	0.26	-0.2
3,850,735	-		Rv3432c	0.26	-1.0
3,850,735	-		Rv3432c	0.26	-0.2
3,850,736	+		Rv3432c	0.26	-0.2
3,850,766	+		Rv3432c	0.28	+0.1
3,850,766	+		Rv3432c	0.28	+1.6
3,850,766	+		Rv3432c	0.28	-0.4
3,850,767	-		Rv3432c	0.29	-1.3
3,850,769	+		Rv3432c	0.29	-0.1
3,850,769	+		Rv3432c	0.29	-0.2
3,850,769	+		Rv3432c	0.29	+0.4
3,850,839	-		Rv3432c	0.34	+0.1
3,850,910	+		Rv3432c	0.39	+0.2
3,850,922	+		Rv3432c	0.40	-0.1
3,851,032	+		Rv3432c	0.48	-1.7
3,851,032	+		Rv3432c	0.48	+0.0
3,851,033	-		Rv3432c	0.48	-0.6
3,851,112	+		Rv3432c	0.54	-0.8
3,851,113	-		Rv3432c	0.54	+1.0
3,851,114	+		Rv3432c	0.54	-0.5
3,851,114	+		Rv3432c	0.54	-0.4
3,851,114	+		Rv3432c	0.54	-1.5
3,851,115	-		Rv3432c	0.54	-0.6
3,851,115	-		Rv3432c	0.54	-0.2
3,851,115	-		Rv3432c	0.54	+0.1