Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3309c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
3,695,578	-		Rv3308	0.44	+0.4
3,696,142	+		Rv3308	0.80	-0.5
3,696,364	+				+0.7
3,696,523	-				-1.5
3,696,523	-				-0.6
3,696,726	-		Rv3309c	0.41	-1.0
3,696,972	+		Rv3309c	0.80	+0.5
3,696,972	+		Rv3309c	0.80	+1.7
3,696,972	+		Rv3309c	0.80	+0.6
3,696,973	-		Rv3309c	0.81	-0.2
3,697,107	-				-0.7
3,697,107	-				+2.3
3,697,107	-				+0.2
3,697,109	-				-1.0
3,697,109	-				-0.7
3,697,110	+				-0.3
3,697,111	-				+1.5
3,697,111	-				+1.0
3,697,111	-				+0.1
3,697,187	-				-0.3
3,697,187	-				-0.6
3,697,188	+				-0.7
3,697,189	-				+2.0
3,697,189	-				+0.3
3,697,241	+				-0.7
3,697,597	+		Rv3310	0.44	+0.4
3,697,663	+		Rv3310	0.52	-1.6
3,697,698	+		Rv3310	0.56	-0.0
3,697,754	-		Rv3310	0.62	-1.0
3,697,861	+		Rv3310	0.74	-1.0
3,697,862	-		Rv3310	0.74	+2.1
3,697,982	-		Rv3310	0.87	-1.8
3,698,032	+				-0.3
3,698,032	+				-0.2
3,698,076	-				-1.0