Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3058c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
3,417,744	-				+0.2
3,417,744	-				-0.1
3,417,860	+				-0.8
3,417,860	+				-0.7
3,417,861	-				-1.0
3,417,891	-		Rv3057c	0.11	+0.2
3,417,891	-		Rv3057c	0.11	-0.5
3,417,915	+		Rv3057c	0.13	-0.8
3,417,915	+		Rv3057c	0.13	-0.5
3,417,915	+		Rv3057c	0.13	-0.3
3,417,915	+		Rv3057c	0.13	-1.0
3,417,915	+		Rv3057c	0.13	+0.6
3,417,915	+		Rv3057c	0.13	-0.3
3,417,916	-		Rv3057c	0.14	+1.5
3,417,916	-		Rv3057c	0.14	-1.3
3,417,916	-		Rv3057c	0.14	+0.5
3,417,918	-		Rv3057c	0.14	-0.2
3,417,926	+		Rv3057c	0.15	-0.3
3,417,926	+		Rv3057c	0.15	-0.8
3,417,927	-		Rv3057c	0.15	+0.4
3,417,927	-		Rv3057c	0.15	-0.7
3,417,927	-		Rv3057c	0.15	+0.2
3,417,927	-		Rv3057c	0.15	-0.5
3,417,927	-		Rv3057c	0.15	+0.2
3,418,056	+		Rv3057c	0.30	-0.2
3,418,056	+		Rv3057c	0.30	-1.0
3,418,173	+		Rv3057c	0.43	+0.5
3,418,174	-		Rv3057c	0.43	-1.3
3,418,175	+		Rv3057c	0.44	-0.4
3,418,175	+		Rv3057c	0.44	+0.1
3,418,378	+		Rv3057c	0.67	-0.0
3,418,378	-		Rv3057c	0.67	+0.7
3,418,382	-		Rv3057c	0.67	+0.4
3,418,382	-		Rv3057c	0.67	-0.5
3,418,442	+		Rv3057c	0.74	-0.3
3,418,545	-		Rv3057c	0.86	+0.3
3,418,545	-		Rv3057c	0.86	+0.5
3,418,637	+				-0.8
3,418,638	-				-0.4
3,418,702	-				+0.8
3,418,727	+				-0.7
3,418,727	+				-0.7
3,418,727	+				-0.2
3,418,727	+				+1.2
3,418,728	-				+0.8
3,418,728	-				-0.6
3,418,728	-				+0.4
3,418,728	-				+1.9
3,418,728	-				+0.1
3,418,728	-				+0.1
3,418,852	-		Rv3058c	0.19	+0.9
3,419,013	+		Rv3058c	0.44	+1.1
3,419,014	-		Rv3058c	0.44	-0.2
3,419,180	+		Rv3058c	0.70	+0.9
3,419,196	-		Rv3058c	0.72	-0.1
3,419,202	-		Rv3058c	0.73	+0.7
3,419,202	-		Rv3058c	0.73	+0.2
3,419,454	+				+0.0
3,419,454	+				+1.0
3,419,455	-				-1.5
3,419,466	-				-1.7
3,419,480	+				+0.9
3,419,517	-				-0.2
3,419,726	+		Rv3059	0.16	+1.7
3,419,741	+		Rv3059	0.17	-0.1
3,419,828	+		Rv3059	0.23	-0.2
3,419,982	-		Rv3059	0.33	+0.1
3,420,260	+		Rv3059	0.52	+0.1