Experiment: 7H9 with Delamanid 0.236 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3018c and Rv3018A are separated by 85 nucleotides Rv3018A and Rv3019c are separated by 295 nucleotides Rv3019c and Rv3020c are separated by 34 nucleotides Rv3020c and Rv3021c are separated by 46 nucleotides
Rv3018c: Rv3018c - PPE family protein PPE46, at 3,376,939 to 3,378,243
Rv3018c
Rv3018A: Rv3018A - PE family protein PE27A, at 3,378,329 to 3,378,415
Rv3018A
Rv3019c: Rv3019c - Secreted ESAT-6 like protein EsxR (TB10.3) (ESAT-6 like protein 9), at 3,378,711 to 3,379,001
Rv3019c
Rv3020c: Rv3020c - ESAT-6 like protein EsxS, at 3,379,036 to 3,379,329
Rv3020c
Rv3021c: Rv3021c - PPE family protein PPE47, at 3,379,376 to 3,380,452
Rv3021c
Position (kb)
3379
3380 Strain fitness (log2 ratio)
-2
-1
0
1 at 3378.433 kb on + strand at 3378.482 kb on + strand at 3378.486 kb on + strand at 3378.507 kb on - strand at 3378.817 kb on - strand, within Rv3019c at 3378.850 kb on + strand, within Rv3019c at 3378.850 kb on + strand, within Rv3019c at 3378.851 kb on - strand, within Rv3019c at 3378.851 kb on - strand, within Rv3019c at 3378.851 kb on - strand, within Rv3019c at 3378.986 kb on - strand at 3378.986 kb on - strand at 3378.986 kb on - strand at 3378.986 kb on - strand at 3379.037 kb on + strand at 3379.050 kb on - strand at 3379.082 kb on + strand, within Rv3020c at 3379.083 kb on - strand, within Rv3020c at 3379.132 kb on - strand, within Rv3020c at 3379.248 kb on + strand, within Rv3020c at 3379.269 kb on + strand, within Rv3020c at 3379.893 kb on - strand, within Rv3021c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Delamanid 0.236 ug/mL remove 3,378,433 + +0.7 3,378,482 + +0.9 3,378,486 + -2.1 3,378,507 - -0.5 3,378,817 - Rv3019c 0.36 -0.4 3,378,850 + Rv3019c 0.48 -0.0 3,378,850 + Rv3019c 0.48 -0.1 3,378,851 - Rv3019c 0.48 +1.6 3,378,851 - Rv3019c 0.48 +1.3 3,378,851 - Rv3019c 0.48 -0.1 3,378,986 - -0.6 3,378,986 - -0.3 3,378,986 - -0.3 3,378,986 - -0.2 3,379,037 + -0.5 3,379,050 - -0.4 3,379,082 + Rv3020c 0.16 +0.7 3,379,083 - Rv3020c 0.16 -0.2 3,379,132 - Rv3020c 0.33 +0.9 3,379,248 + Rv3020c 0.72 +1.1 3,379,269 + Rv3020c 0.79 -0.2 3,379,893 - Rv3021c 0.48 +0.9
Or see this region's nucleotide sequence