Experiment: 7H9 with Delamanid 0.236 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2828c and Rv2828A overlap by 4 nucleotides Rv2828A and Rv2829c are separated by 20 nucleotides Rv2829c and Rv2830c overlap by 4 nucleotides Rv2830c and Rv2831 are separated by 46 nucleotides
Rv2828c: Rv2828c - Conserved hypothetical protein, at 3,135,788 to 3,136,333
Rv2828c
Rv2828A: Rv2828A - Conserved hypothetical protein, at 3,136,330 to 3,136,599
Rv2828A
Rv2829c: Rv2829c - Possible toxin VapC22, at 3,136,620 to 3,137,012
Rv2829c
Rv2830c: Rv2830c - Possible antitoxin VapB22, at 3,137,009 to 3,137,224
Rv2830c
Rv2831: Rv2831 - Probable enoyl-CoA hydratase EchA16 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 3,137,271 to 3,138,020
Rv2831
Position (kb) 3136
3137
3138 Strain fitness (log2 ratio) -1
0
1 at 3136.521 kb on - strand, within Rv2828A at 3136.711 kb on + strand, within Rv2829c at 3136.712 kb on - strand, within Rv2829c at 3137.365 kb on + strand, within Rv2831 at 3137.593 kb on - strand, within Rv2831 at 3137.740 kb on - strand, within Rv2831
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Delamanid 0.236 ug/mL remove 3,136,521 - Rv2828A 0.71 +0.3 3,136,711 + Rv2829c 0.23 -0.3 3,136,712 - Rv2829c 0.23 +0.8 3,137,365 + Rv2831 0.13 -0.5 3,137,593 - Rv2831 0.43 +0.6 3,137,740 - Rv2831 0.63 -0.6
Or see this region's nucleotide sequence