Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2819c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
3,125,372	+		Rv2818c	0.33	-1.0
3,125,419	-		Rv2818c	0.37	-0.4
3,125,663	+		Rv2818c	0.58	-0.1
3,126,038	+				-0.9
3,126,038	+				-0.9
3,126,038	+				+0.1
3,126,038	+				-0.6
3,126,038	+				-0.0
3,126,039	-				-0.0
3,126,151	+				-2.0
3,126,151	+				-0.4
3,126,151	+				-0.7
3,126,284	-				+0.2
3,126,289	-				-0.4
3,126,289	-				-0.2
3,126,289	-				-1.6
3,126,363	+		Rv2819c	0.11	+0.3
3,126,471	+		Rv2819c	0.20	-0.8
3,126,490	+		Rv2819c	0.22	+1.5
3,126,923	-		Rv2819c	0.61	+1.0
3,127,014	-		Rv2819c	0.69	-0.4
3,127,103	+		Rv2819c	0.77	+0.9
3,127,104	-		Rv2819c	0.77	-0.5
3,127,394	+				-0.3
3,127,414	-				+1.0
3,127,414	-				-0.4
3,127,530	+		Rv2820c	0.18	-0.6
3,127,550	+		Rv2820c	0.20	+1.3
3,127,573	-		Rv2820c	0.23	+0.7
3,127,617	-		Rv2820c	0.28	+0.1
3,128,175	+		Rv2820c	0.89	+1.0
3,128,176	-		Rv2820c	0.89	+0.5
3,128,176	-		Rv2820c	0.89	-0.8
3,128,197	+				+0.4
3,128,198	-				-0.7
3,128,254	+				-1.6