Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2692

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
3,009,223	-				-1.0
3,009,408	+				-2.1
3,009,641	+		Rv2691	0.43	-1.0
3,009,665	+		Rv2691	0.47	-1.1
3,009,665	+		Rv2691	0.47	-1.7
3,009,665	+		Rv2691	0.47	+0.4
3,009,666	-		Rv2691	0.47	-2.2
3,009,691	+		Rv2691	0.51	-1.1
3,009,801	+		Rv2691	0.67	+0.3
3,009,892	-		Rv2691	0.80	+0.7
3,009,928	+		Rv2691	0.85	-1.9
3,009,935	+		Rv2691	0.86	-1.1
3,009,936	-		Rv2691	0.87	-2.2
3,009,936	-		Rv2691	0.87	-1.0
3,009,938	-		Rv2691	0.87	-0.7
3,009,938	-		Rv2691	0.87	-2.5
3,010,031	+				-1.8
3,010,031	+				-1.9
3,010,032	-				-1.7
3,010,472	+		Rv2692	0.68	-0.9
3,010,797	+		Rv2693c	0.15	-0.0
3,010,797	+		Rv2693c	0.15	-0.6
3,010,798	-		Rv2693c	0.15	-0.3
3,010,881	+		Rv2693c	0.27	+0.2
3,011,014	-		Rv2693c	0.47	-0.6
3,011,021	+		Rv2693c	0.48	-1.1
3,011,122	-		Rv2693c	0.63	-1.5
3,011,301	+				+2.6
3,011,302	-				-0.4
3,011,359	+				-0.7
3,011,427	+				-1.6
3,011,428	-				-0.2
3,011,428	-				-2.3
3,011,428	-				-2.7
3,011,428	-				-1.3
3,011,431	+				-2.0
3,011,432	-				-1.6
3,011,605	+		Rv2694c	0.56	-1.6