Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2661c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
2,980,394	+		Rv2659c	0.62	-0.4
2,980,395	-		Rv2659c	0.62	-0.8
2,980,440	-		Rv2659c	0.66	-0.0
2,980,527	-		Rv2659c	0.74	-0.9
2,980,580	+		Rv2659c	0.79	-0.5
2,980,633	+		Rv2659c	0.84	-0.4
2,980,633	+		Rv2659c	0.84	+0.5
2,980,633	+		Rv2659c	0.84	+2.0
2,980,633	+		Rv2659c	0.84	-0.4
2,980,633	+		Rv2659c	0.84	-0.0
2,980,633	+		Rv2659c	0.84	-0.6
2,980,634	-		Rv2659c	0.84	-0.6
2,980,634	-		Rv2659c	0.84	-0.3
2,980,634	-		Rv2659c	0.84	+0.3
2,980,634	-		Rv2659c	0.84	-0.0
2,980,634	-		Rv2659c	0.84	-0.2
2,980,634	-		Rv2659c	0.84	-1.6
2,980,715	+				+0.0
2,980,715	+				-0.3
2,980,715	+				-0.3
2,980,715	+				-1.2
2,980,716	-				+0.1
2,980,740	-				-0.2
2,980,852	+				-0.2
2,981,043	+		Rv2660c	0.35	-0.4
2,981,044	-		Rv2660c	0.36	-0.0
2,981,044	-		Rv2660c	0.36	-0.0
2,981,044	-		Rv2660c	0.36	+0.1
2,981,416	-		Rv2661c	0.59	+0.6
2,981,466	-		Rv2661c	0.72	+2.0
2,981,584	+		Rv2662	0.37	+0.1
2,981,585	-		Rv2662	0.38	+2.7
2,981,627	+		Rv2662	0.53	+0.3
2,981,808	+				-0.4
2,981,809	-				-1.2
2,981,809	-				-0.0
2,981,809	-				+0.3
2,981,809	-				-0.2
2,981,946	+		Rv2663	0.40	+0.1
2,981,947	-		Rv2663	0.40	-0.2
2,981,947	-		Rv2663	0.40	-0.4
2,982,001	+		Rv2663	0.63	-0.4
2,982,002	-		Rv2663	0.64	-0.0
2,982,052	+		Rv2663	0.85	+0.3
2,982,053	-		Rv2663	0.85	+0.2
2,982,053	-		Rv2663	0.85	-0.6
2,982,055	+		Rv2663	0.86	-0.1
2,982,056	-		Rv2663	0.87	+2.0
2,982,069	+				+1.0
2,982,069	+				-0.0
2,982,070	-				-0.2
2,982,092	+				-0.6
2,982,092	+				-0.0
2,982,508	-				+0.1