Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2530A

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
2,853,935	-		Rv2529	0.76	-1.5
2,854,908	-				+0.2
2,855,040	+				-0.1
2,855,122	+				-2.5
2,855,122	+				+0.1
2,855,122	+				-0.2
2,855,122	+				-0.5
2,855,162	-				-0.6
2,855,162	-				-0.3
2,855,241	+		Rv2531c	0.11	-1.3
2,855,314	+		Rv2531c	0.13	+0.0
2,855,323	+		Rv2531c	0.14	-2.2
2,855,400	+		Rv2531c	0.16	-0.2
2,855,445	+		Rv2531c	0.18	-0.7
2,855,524	+		Rv2531c	0.21	-0.0
2,855,525	-		Rv2531c	0.21	-0.4
2,855,580	-		Rv2531c	0.23	+0.2
2,855,755	+		Rv2531c	0.29	-0.2
2,855,756	-		Rv2531c	0.29	-0.4
2,855,878	+		Rv2531c	0.33	+0.9
2,855,878	+		Rv2531c	0.33	+0.0
2,855,878	+		Rv2531c	0.33	-0.7
2,855,879	-		Rv2531c	0.33	+0.2
2,855,879	-		Rv2531c	0.33	-0.5