Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2430c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
2,726,812	-				-0.7
2,726,957	+		Rv2429	0.28	-0.9
2,727,236	+		Rv2429	0.81	-0.5
2,727,326	+				+0.6
2,727,327	-				-0.7
2,727,327	-				-0.1
2,727,338	-				-0.1
2,727,463	+		Rv2430c	0.22	+0.1
2,727,464	-		Rv2430c	0.22	+0.5
2,727,464	-		Rv2430c	0.22	+0.0
2,727,506	-		Rv2430c	0.29	-0.2
2,727,593	-		Rv2430c	0.44	+1.1
2,727,615	-		Rv2430c	0.48	+0.1
2,727,634	+		Rv2430c	0.51	-0.5
2,727,634	+		Rv2430c	0.51	+0.1
2,727,874	+				-1.3
2,727,875	-				+0.2
2,727,876	+				-0.2
2,727,877	-				-0.1
2,727,877	-				+0.2
2,727,877	-				-1.1
2,727,969	-				-1.1
2,728,007	+		Rv2431c	0.13	+0.5
2,728,007	+		Rv2431c	0.13	-0.1
2,728,008	-		Rv2431c	0.14	+0.9
2,728,008	-		Rv2431c	0.14	+0.8
2,728,008	-		Rv2431c	0.14	-0.1
2,728,008	-		Rv2431c	0.14	+0.3
2,728,008	-		Rv2431c	0.14	+0.1
2,728,083	-		Rv2431c	0.39	-0.2
2,728,094	+		Rv2431c	0.42	-0.2
2,728,379	+				-0.1
2,728,379	+				+0.1
2,728,383	+				-0.7
2,728,384	-				+0.9
2,728,498	+		Rv2432c	0.15	-0.2
2,728,504	-		Rv2432c	0.16	+0.9
2,728,681	-		Rv2432c	0.59	-1.4