Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2344c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
2,622,524	+				-0.0
2,622,580	-				+0.1
2,622,596	+		Rv2344c	0.11	-0.2
2,622,597	-		Rv2344c	0.11	-0.0
2,622,654	+		Rv2344c	0.15	+0.1
2,622,749	-		Rv2344c	0.23	+0.4
2,622,903	-		Rv2344c	0.34	+1.3
2,623,248	-		Rv2344c	0.61	-0.5
2,623,422	-		Rv2344c	0.74	-0.3
2,623,447	+		Rv2344c	0.76	+1.2
2,623,551	+		Rv2344c	0.84	-0.2
2,623,653	-				-0.8
2,623,653	-				-0.1
2,623,820	+				-1.4
2,623,821	-				+0.1
2,623,821	-				-0.1
2,623,857	-				+0.2
2,623,923	+				+0.1
2,623,924	-				-1.7
2,623,995	+				-1.3
2,624,028	+		Rv2345	0.10	-0.3
2,624,028	+		Rv2345	0.10	+0.6
2,624,028	+		Rv2345	0.10	+1.5
2,624,028	+		Rv2345	0.10	-0.9
2,624,029	-		Rv2345	0.10	+0.2
2,624,029	-		Rv2345	0.10	-0.3
2,624,029	-		Rv2345	0.10	-0.2
2,624,029	-		Rv2345	0.10	+0.0
2,624,099	+		Rv2345	0.14	+0.2
2,624,100	-		Rv2345	0.14	+0.2
2,624,103	+		Rv2345	0.14	-0.4
2,624,103	+		Rv2345	0.14	+1.0
2,624,103	+		Rv2345	0.14	+0.8
2,624,104	-		Rv2345	0.14	-0.6
2,624,104	-		Rv2345	0.14	-0.5
2,624,104	-		Rv2345	0.14	+0.3
2,624,142	+		Rv2345	0.16	+0.0
2,624,152	+		Rv2345	0.17	-0.6
2,624,152	+		Rv2345	0.17	-0.4
2,624,152	+		Rv2345	0.17	+0.2
2,624,153	-		Rv2345	0.17	-1.0
2,624,153	-		Rv2345	0.17	-0.0
2,624,242	-		Rv2345	0.21	+1.0
2,624,426	+		Rv2345	0.31	+0.2
2,624,434	+		Rv2345	0.31	+0.1
2,624,435	-		Rv2345	0.31	-0.5
2,624,494	+		Rv2345	0.34	+0.4
2,624,495	-		Rv2345	0.34	-0.1
2,624,495	-		Rv2345	0.34	-0.0
2,624,684	-		Rv2345	0.44	-0.0