Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2058c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
2,313,836	+				-0.4
2,313,836	+				+0.3
2,313,836	+				+0.0
2,313,837	-				+1.6
2,313,837	-				-0.8
2,313,840	+				-0.2
2,313,840	+				+0.3
2,313,841	-				-0.2
2,313,841	-				-0.2
2,313,841	-				+0.7
2,313,953	-				+0.1
2,313,953	-				-0.1
2,313,953	-				-0.9
2,313,953	-				-0.5
2,314,131	-		Rv2055c	0.16	-0.3
2,314,271	+		Rv2055c	0.69	+1.0
2,314,356	-				-0.1
2,314,738	+		Rv2057c	0.47	-0.0
2,314,739	-		Rv2057c	0.47	+0.3
2,314,761	+		Rv2057c	0.61	-0.4
2,314,761	+		Rv2057c	0.61	-0.5
2,314,761	+		Rv2057c	0.61	+0.4
2,314,761	+		Rv2057c	0.61	-0.4
2,314,894	+		Rv2058c	0.29	-0.7
2,314,895	-		Rv2058c	0.30	+0.4
2,314,895	-		Rv2058c	0.30	+0.4
2,314,895	-		Rv2058c	0.30	+0.0
2,314,895	-		Rv2058c	0.30	+0.4
2,314,895	-		Rv2058c	0.30	+0.2
2,314,896	+		Rv2058c	0.30	-0.8
2,314,896	+		Rv2058c	0.30	+0.5
2,314,896	+		Rv2058c	0.30	+0.8
2,314,897	-		Rv2058c	0.30	+3.3
2,314,897	-		Rv2058c	0.30	-0.2
2,314,897	-		Rv2058c	0.30	+0.5
2,314,897	-		Rv2058c	0.30	-0.0
2,314,946	+		Rv2058c	0.51	+0.2
2,314,946	+		Rv2058c	0.51	-1.6
2,314,947	-		Rv2058c	0.51	+0.5
2,314,949	+		Rv2058c	0.52	+0.4
2,314,950	-		Rv2058c	0.53	-1.0
2,314,950	-		Rv2058c	0.53	-0.4
2,315,116	-				-0.2
2,315,116	-				-0.9
2,315,127	+				+0.3
2,315,127	+				-0.5
2,315,128	-				+1.4
2,315,128	-				+0.6
2,315,436	+		Rv2059	0.17	-0.6
2,315,455	+		Rv2059	0.18	+1.5
2,315,456	-		Rv2059	0.18	-0.0
2,315,541	+		Rv2059	0.24	+0.4
2,315,541	+		Rv2059	0.24	-0.7
2,315,542	-		Rv2059	0.24	-0.2
2,315,542	-		Rv2059	0.24	-0.1
2,315,589	-		Rv2059	0.27	-0.2
2,315,589	-		Rv2059	0.27	+0.1
2,315,642	+		Rv2059	0.30	+0.5
2,315,642	+		Rv2059	0.30	-0.0
2,315,643	-		Rv2059	0.31	+0.4
2,315,717	+		Rv2059	0.35	+0.0
2,315,718	-		Rv2059	0.35	-0.2
2,315,771	+		Rv2059	0.39	-0.2
2,315,772	-		Rv2059	0.39	+0.6
2,315,772	-		Rv2059	0.39	-0.5
2,315,853	-		Rv2059	0.44	+0.2
2,315,928	-		Rv2059	0.49	+0.4
2,315,969	+		Rv2059	0.52	-0.6
2,315,970	-		Rv2059	0.52	+0.1
2,315,970	-		Rv2059	0.52	+0.1
2,315,970	-		Rv2059	0.52	+0.9