Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2043c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
2,287,874	-				-0.2
2,288,108	-		Rv2042c	0.28	-0.5
2,288,233	-		Rv2042c	0.44	-0.1
2,288,372	-		Rv2042c	0.61	+2.6
2,288,376	+		Rv2042c	0.62	+0.3
2,288,376	+		Rv2042c	0.62	-2.0
2,288,846	-		Rv2043c	0.29	-0.2
2,288,958	+		Rv2043c	0.49	+0.6
2,289,141	+		Rv2043c	0.82	+0.1
2,289,241	+				+0.2
2,289,241	+				-0.3
2,289,242	-				-0.3
2,289,252	+				-0.6
2,289,253	-				-0.8
2,289,306	+				+0.3
2,289,307	-				-0.4
2,289,391	+		Rv2044c	0.34	+0.2
2,289,578	-				+0.4
2,289,612	+				-0.6
2,289,794	+				+0.1
2,289,926	+		Rv2045c	0.16	-0.4
2,290,007	+		Rv2045c	0.21	+1.0
2,290,013	+		Rv2045c	0.21	-0.8
2,290,019	+		Rv2045c	0.22	-0.5
2,290,020	-		Rv2045c	0.22	-0.0
2,290,020	-		Rv2045c	0.22	-0.5
2,290,175	-		Rv2045c	0.32	-0.8