Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1888c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
2,136,520	+		Rv1887	0.23	-0.1
2,136,572	-		Rv1887	0.27	-0.4
2,136,950	-		Rv1887	0.61	-0.8
2,137,002	+		Rv1887	0.65	-0.3
2,137,139	+		Rv1887	0.77	-1.1
2,137,360	+				-0.9
2,137,361	-				-0.0
2,137,361	-				+0.2
2,137,372	-				-0.6
2,137,491	+				-0.0
2,137,492	-				-0.4
2,137,492	-				-0.9
2,137,529	+				+0.7
2,137,529	+				-0.5
2,137,530	-				-1.4
2,137,530	-				-0.6
2,137,530	-				+0.1
2,137,530	-				-1.6
2,137,530	-				+0.4
2,137,530	-				+2.4
2,137,531	+				-0.1
2,137,531	+				+0.1
2,137,532	-				+3.0
2,137,537	+				+0.2
2,137,613	-		Rv1888c	0.17	+1.0
2,137,685	+		Rv1888c	0.30	-0.5
2,137,685	+		Rv1888c	0.30	+0.1
2,137,686	-		Rv1888c	0.30	-0.5
2,137,696	-		Rv1888c	0.32	-0.0
2,137,702	+		Rv1888c	0.33	-0.2
2,137,702	+		Rv1888c	0.33	+0.7
2,137,713	+		Rv1888c	0.35	+0.0
2,137,713	+		Rv1888c	0.35	-0.0
2,137,749	-		Rv1888c	0.41	+0.4
2,137,773	-		Rv1888c	0.45	+0.4
2,137,835	+		Rv1888c	0.56	+0.2
2,137,835	+		Rv1888c	0.56	-0.3
2,137,899	-		Rv1888c	0.68	+0.8
2,137,899	-		Rv1888c	0.68	+0.0
2,137,899	-		Rv1888c	0.68	+0.3
2,137,980	-		Rv1888c	0.82	+0.3
2,138,008	+		Rv1888c	0.87	+0.5
2,138,095	+				+2.0
2,138,095	+				-0.5
2,138,096	-				-0.1
2,138,096	-				-1.0
2,138,096	-				-0.2
2,138,175	+				+1.0
2,138,176	-				+0.1
2,138,202	+				-0.6
2,138,215	+				-0.1
2,138,215	+				+0.2
2,138,250	-				+0.4
2,138,349	+				+0.4
2,138,446	-				-0.2
2,138,446	-				+0.2
2,138,979	-		Rv1889c	0.89	+0.1
2,138,979	-		Rv1889c	0.89	+1.0
2,139,046	+				+0.2
2,139,046	+				+0.1
2,139,046	+				+0.0
2,139,047	-				-0.2