Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1664

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
1,887,416	+		Rv1663	0.60	-0.0
1,887,545	+		Rv1663	0.68	+1.0
1,887,545	+		Rv1663	0.68	-0.7
1,887,549	-		Rv1663	0.69	+0.2
1,887,549	-		Rv1663	0.69	-0.3
1,887,549	-		Rv1663	0.69	-0.5
1,887,553	-		Rv1663	0.69	+0.8
1,887,825	-		Rv1663	0.87	-0.3
1,888,608	-		Rv1664	0.19	-0.1
1,888,611	+		Rv1664	0.19	-1.3
1,888,642	+		Rv1664	0.20	-1.2
1,888,851	+		Rv1664	0.27	-0.7
1,888,852	-		Rv1664	0.27	-0.4
1,888,852	-		Rv1664	0.27	-0.6
1,889,024	-		Rv1664	0.33	-0.2
1,890,226	-		Rv1664	0.72	-0.4
1,890,241	-		Rv1664	0.73	-0.6
1,890,368	-		Rv1664	0.77	-0.9
1,890,495	+		Rv1664	0.81	-0.2
1,890,523	+		Rv1664	0.82	-1.1
1,890,911	+				-0.4
1,890,912	-				-0.8
1,891,070	+				-0.2
1,891,111	+				-0.4
1,891,207	-				-0.8
1,891,401	-		Rv1665	0.16	-0.3
1,891,677	-		Rv1665	0.42	+0.2
1,891,740	-		Rv1665	0.48	-0.2
1,891,980	-		Rv1665	0.71	-1.0