Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0927c

Experiment: 7H9 with Delamanid 0.236 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0926c and Rv0927c are separated by 53 nucleotidesRv0927c and Rv0928 are separated by 271 nucleotides Rv0926c: Rv0926c - Conserved hypothetical protein, at 1,032,710 to 1,033,786 Rv0926c Rv0927c: Rv0927c - Probable short-chain type dehydrogenase/reductase, at 1,033,840 to 1,034,631 Rv0927c Rv0928: Rv0928 - Periplasmic phosphate-binding lipoprotein PstS3 (PBP-3) (PstS3) (PHOS1), at 1,034,903 to 1,036,015 Rv0928 Position (kb) 1033 1034 1035Strain fitness (log2 ratio) -2 -1 0 1at 1032.885 kb on + strand, within Rv0926cat 1032.886 kb on - strand, within Rv0926cat 1032.956 kb on + strand, within Rv0926cat 1033.060 kb on + strand, within Rv0926cat 1033.257 kb on - strand, within Rv0926cat 1033.301 kb on + strand, within Rv0926cat 1033.302 kb on - strand, within Rv0926cat 1033.489 kb on + strand, within Rv0926cat 1033.518 kb on + strand, within Rv0926cat 1033.563 kb on + strand, within Rv0926cat 1033.940 kb on + strand, within Rv0927cat 1034.153 kb on + strand, within Rv0927cat 1034.665 kb on + strandat 1034.726 kb on - strandat 1034.737 kb on - strandat 1034.853 kb on + strandat 1035.144 kb on - strand, within Rv0928at 1035.312 kb on - strand, within Rv0928at 1035.382 kb on + strand, within Rv0928at 1035.382 kb on + strand, within Rv0928at 1035.500 kb on + strand, within Rv0928at 1035.532 kb on + strand, within Rv0928

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Delamanid 0.236 ug/mL
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1,032,885 + Rv0926c 0.16 -0.3
1,032,886 - Rv0926c 0.16 -0.6
1,032,956 + Rv0926c 0.23 -0.0
1,033,060 + Rv0926c 0.32 -0.4
1,033,257 - Rv0926c 0.51 +1.0
1,033,301 + Rv0926c 0.55 -0.9
1,033,302 - Rv0926c 0.55 +0.3
1,033,489 + Rv0926c 0.72 -0.1
1,033,518 + Rv0926c 0.75 -1.5
1,033,563 + Rv0926c 0.79 -0.5
1,033,940 + Rv0927c 0.13 +0.3
1,034,153 + Rv0927c 0.40 +1.1
1,034,665 + -0.9
1,034,726 - -0.1
1,034,737 - -0.1
1,034,853 + +0.1
1,035,144 - Rv0928 0.22 -0.7
1,035,312 - Rv0928 0.37 -1.8
1,035,382 + Rv0928 0.43 -1.2
1,035,382 + Rv0928 0.43 -0.8
1,035,500 + Rv0928 0.54 -0.7
1,035,532 + Rv0928 0.57 -1.8

Or see this region's nucleotide sequence