Experiment: 7H9 with Delamanid 0.236 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0787A and Rv0788 overlap by 4 nucleotides Rv0788 and Rv0789c are separated by 16 nucleotides Rv0789c and Rv0790c are separated by 21 nucleotides Rv0790c and Rv0791c overlap by 4 nucleotides
Rv0787A: Rv0787A - Conserved protein, at 882,524 to 882,763
Rv0787A
Rv0788: Rv0788 - Probable phosphoribosylformylglycinamidine synthase I PURG (FGAM synthase I), at 882,760 to 883,434
Rv0788
Rv0789c: Rv0789c - Hypothetical protein, at 883,451 to 884,050
Rv0789c
Rv0790c: Rv0790c - Hypothetical protein, at 884,072 to 884,800
Rv0790c
Rv0791c: Rv0791c - Conserved protein, at 884,797 to 885,840
Rv0791c
Position (kb)
883
884
885 Strain fitness (log2 ratio)
-2
-1
0
1 at 883.493 kb on + strand at 883.493 kb on + strand at 883.728 kb on + strand, within Rv0789c at 883.782 kb on - strand, within Rv0789c at 883.875 kb on + strand, within Rv0789c at 884.150 kb on + strand, within Rv0790c at 884.151 kb on - strand, within Rv0790c at 884.232 kb on + strand, within Rv0790c at 884.232 kb on + strand, within Rv0790c at 884.376 kb on + strand, within Rv0790c at 884.376 kb on + strand, within Rv0790c at 884.376 kb on + strand, within Rv0790c at 884.376 kb on + strand, within Rv0790c at 884.376 kb on + strand, within Rv0790c at 884.377 kb on - strand, within Rv0790c at 884.632 kb on - strand, within Rv0790c at 884.649 kb on + strand, within Rv0790c at 884.649 kb on + strand, within Rv0790c at 884.650 kb on - strand, within Rv0790c at 884.652 kb on + strand, within Rv0790c at 884.653 kb on - strand, within Rv0790c at 884.655 kb on + strand, within Rv0790c at 884.655 kb on + strand, within Rv0790c at 884.656 kb on - strand, within Rv0790c at 884.745 kb on + strand at 884.745 kb on + strand at 884.746 kb on - strand at 884.859 kb on - strand at 884.859 kb on - strand at 884.918 kb on + strand, within Rv0791c at 884.919 kb on - strand, within Rv0791c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Delamanid 0.236 ug/mL remove 883,493 + -2.4 883,493 + -0.4 883,728 + Rv0789c 0.46 +0.2 883,782 - Rv0789c 0.55 +0.5 883,875 + Rv0789c 0.71 -0.3 884,150 + Rv0790c 0.11 +0.6 884,151 - Rv0790c 0.11 +0.1 884,232 + Rv0790c 0.22 +0.9 884,232 + Rv0790c 0.22 -0.8 884,376 + Rv0790c 0.42 -0.6 884,376 + Rv0790c 0.42 -0.8 884,376 + Rv0790c 0.42 -0.7 884,376 + Rv0790c 0.42 -0.0 884,376 + Rv0790c 0.42 -0.4 884,377 - Rv0790c 0.42 -0.8 884,632 - Rv0790c 0.77 -0.6 884,649 + Rv0790c 0.79 -0.0 884,649 + Rv0790c 0.79 -0.0 884,650 - Rv0790c 0.79 +0.3 884,652 + Rv0790c 0.80 +0.2 884,653 - Rv0790c 0.80 +0.2 884,655 + Rv0790c 0.80 -0.1 884,655 + Rv0790c 0.80 +0.3 884,656 - Rv0790c 0.80 -0.8 884,745 + -0.3 884,745 + -0.1 884,746 - +0.1 884,859 - +0.0 884,859 - +0.3 884,918 + Rv0791c 0.12 -1.0 884,919 - Rv0791c 0.12 -0.5
Or see this region's nucleotide sequence