Experiment: 7H9 with Delamanid 0.236 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0764c and Rv0765c overlap by 1 nucleotides Rv0765c and Rv0766c overlap by 1 nucleotides Rv0766c and Rv0767c overlap by 4 nucleotides Rv0767c and Rv0768 are separated by 201 nucleotides
Rv0764c: Rv0764c - Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM), at 856,682 to 858,037
Rv0764c
Rv0765c: Rv0765c - Probable oxidoreductase, at 858,037 to 858,864
Rv0765c
Rv0766c: Rv0766c - Probable cytochrome P450 123 Cyp123, at 858,864 to 860,072
Rv0766c
Rv0767c: Rv0767c - Conserved hypothetical protein, at 860,069 to 860,710
Rv0767c
Rv0768: Rv0768 - Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]), at 860,912 to 862,381
Rv0768
Position (kb) 858
859
860
861 Strain fitness (log2 ratio) -2
-1
0
1 at 858.390 kb on - strand, within Rv0765c at 858.514 kb on + strand, within Rv0765c at 858.865 kb on + strand at 859.229 kb on - strand, within Rv0766c at 859.492 kb on + strand, within Rv0766c at 859.867 kb on - strand, within Rv0766c at 860.030 kb on - strand at 860.099 kb on - strand at 860.127 kb on + strand at 860.154 kb on + strand, within Rv0767c at 860.180 kb on + strand, within Rv0767c at 860.466 kb on + strand, within Rv0767c at 860.502 kb on + strand, within Rv0767c at 860.502 kb on + strand, within Rv0767c at 860.502 kb on + strand, within Rv0767c at 860.503 kb on - strand, within Rv0767c at 860.508 kb on + strand, within Rv0767c at 860.508 kb on + strand, within Rv0767c at 860.508 kb on + strand, within Rv0767c at 860.603 kb on + strand, within Rv0767c at 860.604 kb on - strand, within Rv0767c at 860.909 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Delamanid 0.236 ug/mL remove 858,390 - Rv0765c 0.43 -0.1 858,514 + Rv0765c 0.58 +0.1 858,865 + -0.7 859,229 - Rv0766c 0.30 -0.2 859,492 + Rv0766c 0.52 +1.5 859,867 - Rv0766c 0.83 +0.9 860,030 - +0.1 860,099 - -0.1 860,127 + -2.5 860,154 + Rv0767c 0.13 -0.4 860,180 + Rv0767c 0.17 +0.0 860,466 + Rv0767c 0.62 +0.9 860,502 + Rv0767c 0.67 -0.2 860,502 + Rv0767c 0.67 +1.5 860,502 + Rv0767c 0.67 -0.1 860,503 - Rv0767c 0.68 -0.2 860,508 + Rv0767c 0.68 -0.2 860,508 + Rv0767c 0.68 +1.2 860,508 + Rv0767c 0.68 +0.2 860,603 + Rv0767c 0.83 -0.2 860,604 - Rv0767c 0.83 -0.2 860,909 + -0.3
Or see this region's nucleotide sequence