Experiment: 7H9 with Delamanid 0.236 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0609 and Rv0609A overlap by 58 nucleotides Rv0609A and Rv0610c are separated by 694 nucleotides Rv0610c and Rv0611c are separated by 51 nucleotides Rv0611c and Rv0612 overlap by 21 nucleotides
Rv0609: Rv0609 - Possible toxin VapC28. Contains PIN domain., at 703,486 to 703,887
Rv0609
Rv0609A: Rv0609A - Conserved hypothetical protein, at 703,830 to 704,057
Rv0609A
Rv0610c: Rv0610c - Hypothetical protein, at 704,752 to 705,909
Rv0610c
Rv0611c: Rv0611c - Hypothetical protein, at 705,961 to 706,344
Rv0611c
Rv0612: Rv0612 - Conserved hypothetical protein, at 706,324 to 706,929
Rv0612
Position (kb) 704
705
706 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 703.796 kb on - strand, within Rv0609 at 703.796 kb on - strand, within Rv0609 at 703.927 kb on - strand, within Rv0609A at 704.175 kb on + strand at 704.175 kb on + strand at 704.175 kb on + strand at 704.176 kb on - strand at 704.176 kb on - strand at 704.366 kb on + strand at 704.367 kb on - strand at 704.440 kb on + strand at 704.509 kb on + strand at 704.520 kb on - strand at 704.520 kb on - strand at 705.533 kb on + strand, within Rv0610c at 705.799 kb on + strand at 705.833 kb on - strand at 705.887 kb on - strand at 705.895 kb on + strand at 705.963 kb on - strand at 705.963 kb on - strand at 706.063 kb on - strand, within Rv0611c at 706.153 kb on + strand, within Rv0611c at 706.153 kb on + strand, within Rv0611c at 706.178 kb on + strand, within Rv0611c at 706.178 kb on + strand, within Rv0611c at 706.178 kb on + strand, within Rv0611c at 706.179 kb on - strand, within Rv0611c at 706.179 kb on - strand, within Rv0611c at 706.195 kb on - strand, within Rv0611c at 706.195 kb on - strand, within Rv0611c at 706.255 kb on + strand, within Rv0611c at 706.639 kb on + strand, within Rv0612 at 706.640 kb on - strand, within Rv0612 at 706.810 kb on + strand, within Rv0612 at 706.811 kb on - strand, within Rv0612
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Delamanid 0.236 ug/mL remove 703,796 - Rv0609 0.77 +0.1 703,796 - Rv0609 0.77 -0.1 703,927 - Rv0609A 0.43 -0.2 704,175 + -0.1 704,175 + -0.8 704,175 + +1.4 704,176 - -0.1 704,176 - -0.1 704,366 + +0.6 704,367 - -0.6 704,440 + -0.2 704,509 + -0.3 704,520 - -0.6 704,520 - +0.3 705,533 + Rv0610c 0.67 +0.5 705,799 + -3.0 705,833 - +0.9 705,887 - +0.0 705,895 + -0.3 705,963 - +0.2 705,963 - -0.2 706,063 - Rv0611c 0.27 +0.0 706,153 + Rv0611c 0.50 -0.2 706,153 + Rv0611c 0.50 -0.4 706,178 + Rv0611c 0.57 +0.1 706,178 + Rv0611c 0.57 -0.3 706,178 + Rv0611c 0.57 -0.2 706,179 - Rv0611c 0.57 -0.3 706,179 - Rv0611c 0.57 +0.3 706,195 - Rv0611c 0.61 -0.4 706,195 - Rv0611c 0.61 +2.1 706,255 + Rv0611c 0.77 -0.9 706,639 + Rv0612 0.52 +0.1 706,640 - Rv0612 0.52 -0.1 706,810 + Rv0612 0.80 -0.9 706,811 - Rv0612 0.80 +0.2
Or see this region's nucleotide sequence