Experiment: 7H9 with Delamanid 0.236 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0597c and Rv0598c are separated by 250 nucleotides Rv0598c and Rv0599c overlap by 4 nucleotides Rv0599c and Rv0600c are separated by 103 nucleotides Rv0600c and Rv0601c are separated by 113 nucleotides
Rv0597c: Rv0597c - Conserved hypothetical protein, at 695,668 to 696,903
Rv0597c
Rv0598c: Rv0598c - Possible toxin VapC27. Contains PIN domain., at 697,154 to 697,567
Rv0598c
Rv0599c: Rv0599c - Possible antitoxin VapB27, at 697,564 to 697,800
Rv0599c
Rv0600c: Rv0600c - Two component sensor kinase [second part], at 697,904 to 698,410
Rv0600c
Rv0601c: Rv0601c - Two component sensor kinase [first part], at 698,524 to 698,994
Rv0601c
Position (kb) 697
698 Strain fitness (log2 ratio) -2
-1
0
1 at 696.326 kb on + strand, within Rv0597c at 696.327 kb on - strand, within Rv0597c at 696.327 kb on - strand, within Rv0597c at 696.327 kb on - strand, within Rv0597c at 696.327 kb on - strand, within Rv0597c at 696.703 kb on + strand, within Rv0597c at 696.914 kb on + strand at 697.270 kb on - strand, within Rv0598c at 697.366 kb on + strand, within Rv0598c at 697.432 kb on - strand, within Rv0598c at 697.708 kb on + strand, within Rv0599c at 697.806 kb on + strand at 697.905 kb on + strand at 697.916 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Delamanid 0.236 ug/mL remove 696,326 + Rv0597c 0.53 +0.1 696,327 - Rv0597c 0.53 +0.5 696,327 - Rv0597c 0.53 -0.4 696,327 - Rv0597c 0.53 -0.2 696,327 - Rv0597c 0.53 -0.3 696,703 + Rv0597c 0.84 -0.1 696,914 + -1.2 697,270 - Rv0598c 0.28 -1.8 697,366 + Rv0598c 0.51 -0.2 697,432 - Rv0598c 0.67 -1.0 697,708 + Rv0599c 0.61 -0.0 697,806 + +0.2 697,905 + -0.1 697,916 - +0.2
Or see this region's nucleotide sequence