Experiment: 7H9 with Delamanid 0.236 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3664c and Rv3665c are separated by 55 nucleotides Rv3665c and Rv3666c are separated by 1 nucleotides Rv3666c and Rv3667 are separated by 707 nucleotides
Rv3664c: Rv3664c - Probable dipeptide-transport integral membrane protein ABC transporter DppC, at 4,103,675 to 4,104,475
Rv3664c
Rv3665c: Rv3665c - Probable dipeptide-transport integral membrane protein ABC transporter DppB, at 4,104,531 to 4,105,457
Rv3665c
Rv3666c: Rv3666c - Probable periplasmic dipeptide-binding lipoprotein DppA, at 4,105,459 to 4,107,084
Rv3666c
Rv3667: Rv3667 - Acetyl-coenzyme A synthetase Acs (acetate--CoA ligase) (acetyl-CoA synthetase) (acetyl-CoA synthase) (acyl-activating enzyme) (acetate thiokinase) (acetyl-activating enzyme) (acetate--coenzyme A ligase) (acetyl-coenzyme A synthase), at 4,107,792 to 4,109,747
Rv3667
Position (kb)
4105
4106
4107
4108 Strain fitness (log2 ratio)
-1
0
1 at 4104.482 kb on - strand at 4104.482 kb on - strand at 4105.447 kb on + strand at 4105.998 kb on - strand, within Rv3666c at 4106.337 kb on - strand, within Rv3666c at 4106.362 kb on - strand, within Rv3666c at 4106.528 kb on + strand, within Rv3666c at 4106.730 kb on - strand, within Rv3666c at 4106.876 kb on + strand, within Rv3666c at 4107.438 kb on + strand at 4107.439 kb on - strand at 4107.530 kb on + strand at 4107.667 kb on + strand at 4107.695 kb on + strand at 4107.765 kb on + strand at 4107.765 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Delamanid 0.236 ug/mL remove 4,104,482 - -0.2 4,104,482 - -0.7 4,105,447 + +0.4 4,105,998 - Rv3666c 0.33 -0.5 4,106,337 - Rv3666c 0.54 -0.1 4,106,362 - Rv3666c 0.56 -0.1 4,106,528 + Rv3666c 0.66 -0.7 4,106,730 - Rv3666c 0.78 -1.4 4,106,876 + Rv3666c 0.87 +0.9 4,107,438 + +0.6 4,107,439 - -0.2 4,107,530 + +0.9 4,107,667 + -0.6 4,107,695 + -1.0 4,107,765 + -1.1 4,107,765 + -0.7
Or see this region's nucleotide sequence