Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3315c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
3,702,903	+		Rv3314c	0.56	-2.1
3,703,225	+		Rv3314c	0.81	+0.1
3,703,368	+				-0.6
3,703,370	+				+0.3
3,703,370	+				-0.4
3,703,371	-				+0.3
3,703,371	-				-0.2
3,703,714	+		Rv3315c	0.62	-0.5
3,703,714	+		Rv3315c	0.62	-0.6
3,703,805	-		Rv3315c	0.85	-0.9
3,703,805	-		Rv3315c	0.85	+0.6
3,703,805	-		Rv3315c	0.85	-1.0
3,703,844	+				+0.2
3,703,910	+				-0.4
3,704,013	+				-0.1
3,704,084	+				-0.5
3,704,101	+				+0.2
3,704,102	-				+0.7
3,704,116	-				-2.4
3,704,205	-		Rv3316	0.30	-0.7
3,704,263	-		Rv3316	0.47	-0.1
3,704,339	+		Rv3316	0.70	+0.1
3,704,755	+		Rv3317	0.73	-0.7
3,704,836	+				-0.6
3,704,836	+				-0.1
3,704,836	+				-0.7
3,704,844	-				-1.2