Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3261

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
3,639,843	-				-0.4
3,639,843	-				+0.0
3,640,265	-				-0.0
3,640,298	-				-0.8
3,640,530	-				+0.2
3,640,741	+		Rv3261	0.20	+2.5
3,640,742	-		Rv3261	0.20	+1.9
3,640,742	-		Rv3261	0.20	+0.6
3,640,742	-		Rv3261	0.20	+1.6
3,641,003	+		Rv3261	0.46	+3.3
3,641,887	+		Rv3262	0.26	+1.5
3,642,060	+		Rv3262	0.39	+1.0
3,642,061	-		Rv3262	0.39	+1.5
3,642,526	+		Rv3262	0.74	+2.1