Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3139

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
3,504,489	-		Rv3138	0.27	-0.1
3,504,618	+		Rv3138	0.39	-0.0
3,504,619	-		Rv3138	0.39	-0.3
3,504,745	+		Rv3138	0.51	-0.3
3,504,746	-		Rv3138	0.51	-0.5
3,504,769	-		Rv3138	0.53	-0.1
3,504,819	+		Rv3138	0.57	+0.2
3,504,879	-		Rv3138	0.63	+0.7
3,505,158	+		Rv3138	0.88	+0.3
3,505,216	-				+0.3
3,505,216	-				+0.0
3,505,362	+				+0.3
3,505,363	-				-1.4
3,505,419	+				-0.7
3,505,528	+		Rv3139	0.12	-1.5
3,505,565	-		Rv3139	0.14	-0.1
3,505,673	-		Rv3139	0.22	-1.8
3,505,784	-		Rv3139	0.30	-0.8
3,505,825	-		Rv3139	0.33	-0.3
3,505,825	-		Rv3139	0.33	-1.0
3,505,913	-		Rv3139	0.39	-0.7
3,506,178	+		Rv3139	0.58	-1.1
3,506,179	-		Rv3139	0.58	-1.4
3,506,440	+		Rv3139	0.77	-1.3
3,506,689	+				-1.4
3,506,690	-				-0.5
3,506,907	+				-1.0
3,507,046	+		Rv3140	0.21	-1.4
3,507,357	-		Rv3140	0.47	-0.4
3,507,357	-		Rv3140	0.47	-1.3
3,507,612	-		Rv3140	0.68	-1.1
3,507,646	-		Rv3140	0.71	-0.8