Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2693c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
3,009,801	+		Rv2691	0.67	-0.1
3,009,892	-		Rv2691	0.80	+0.6
3,009,928	+		Rv2691	0.85	-1.7
3,009,935	+		Rv2691	0.86	-1.1
3,009,936	-		Rv2691	0.87	-2.4
3,009,936	-		Rv2691	0.87	-1.1
3,009,938	-		Rv2691	0.87	-1.1
3,009,938	-		Rv2691	0.87	-2.6
3,010,031	+				-1.9
3,010,031	+				-1.9
3,010,032	-				-1.2
3,010,472	+		Rv2692	0.68	-2.0
3,010,797	+		Rv2693c	0.15	-0.3
3,010,797	+		Rv2693c	0.15	-0.4
3,010,798	-		Rv2693c	0.15	+0.4
3,010,881	+		Rv2693c	0.27	-1.4
3,011,014	-		Rv2693c	0.47	+0.3
3,011,021	+		Rv2693c	0.48	-0.3
3,011,122	-		Rv2693c	0.63	-1.7
3,011,301	+				+2.9
3,011,302	-				-1.8
3,011,359	+				-0.4
3,011,427	+				-1.7
3,011,428	-				-1.9
3,011,428	-				-2.1
3,011,428	-				-3.7
3,011,428	-				-0.8
3,011,431	+				-2.9
3,011,432	-				-0.5
3,011,605	+		Rv2694c	0.56	-2.4
3,011,691	-		Rv2694c	0.79	-1.9
3,011,691	-		Rv2694c	0.79	-2.2
3,011,751	+				-1.9
3,011,752	-				-1.0
3,011,789	+				-0.7
3,011,789	+				-3.3
3,011,789	+				-0.7
3,011,789	+				+0.3
3,011,789	+				-2.6
3,011,790	-				-0.4
3,011,790	-				-0.3
3,011,790	-				-0.8
3,011,790	-				-0.5
3,011,790	-				-0.8
3,011,790	-				-0.7
3,011,790	-				-1.5
3,011,790	-				-0.6
3,011,790	-				-1.1
3,011,790	-				-0.6
3,011,794	+				-0.4
3,011,821	+				-1.7
3,011,822	-				-0.2
3,011,822	-				-0.5
3,011,830	+				-1.6
3,011,831	-				-0.2
3,011,831	-				-1.1
3,011,847	+				+0.7
3,011,847	+				-1.2
3,011,907	+				-0.7
3,011,908	-				+0.3
3,011,908	-				-0.4
3,011,908	-				+0.2
3,011,908	-				+0.6
3,011,908	-				+0.1
3,011,979	+				+0.0
3,011,979	+				-0.2
3,011,979	+				-1.4
3,011,980	-				-0.4
3,012,226	+		Rv2695	0.44	-0.4
3,012,227	-		Rv2695	0.44	-0.5
3,012,227	-		Rv2695	0.44	-0.1
3,012,314	+		Rv2695	0.56	-0.2
3,012,314	+		Rv2695	0.56	+0.2
3,012,315	-		Rv2695	0.56	-0.2