Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2028c

Experiment: 7H9 with Delamanid 0.236 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Delamanid 0.236 ug/mL
2,273,608	+		Rv2027c	0.48	-1.1
2,273,609	-		Rv2027c	0.48	+0.0
2,273,697	-		Rv2027c	0.53	-0.3
2,273,697	-		Rv2027c	0.53	-2.4
2,273,697	-		Rv2027c	0.53	+0.0
2,274,003	+		Rv2027c	0.71	+0.2
2,274,003	+		Rv2027c	0.71	+0.9
2,274,110	-		Rv2027c	0.77	-0.7
2,274,217	-		Rv2027c	0.83	-0.4
2,274,235	+		Rv2027c	0.84	+1.9
2,274,236	-		Rv2027c	0.84	+0.9
2,274,236	-		Rv2027c	0.84	+0.9
2,274,236	-		Rv2027c	0.84	+0.2
2,274,236	-		Rv2027c	0.84	+0.3
2,274,236	-		Rv2027c	0.84	+0.4
2,274,244	-		Rv2027c	0.85	-1.7
2,274,296	-		Rv2027c	0.88	-0.1
2,274,510	+				+0.6
2,274,511	-				+0.7
2,274,511	-				-0.1
2,274,511	-				-0.7
2,274,511	-				-1.6
2,274,511	-				+0.2
2,274,514	+				+0.0
2,274,514	+				-0.2
2,274,514	+				-0.5
2,274,514	+				-1.5
2,274,515	-				-1.5
2,274,515	-				-0.4
2,274,515	-				-0.4
2,274,515	-				-0.2
2,274,515	-				-0.1
2,274,515	-				+0.8
2,274,515	-				+1.9
2,274,693	-		Rv2028c	0.15	-1.7
2,274,718	-		Rv2028c	0.18	-0.7
2,275,037	-		Rv2028c	0.56	-0.1
2,275,370	-				-0.4
2,275,445	+				-0.1
2,275,446	-				-0.0
2,275,946	+		Rv2029c	0.53	-1.2
2,275,947	-		Rv2029c	0.53	-0.7
2,276,292	-		Rv2029c	0.87	+0.1